Oxygen levels during surgery: does more help or hurt?

NCT ID NCT07525661

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different oxygen levels during laparoscopic lower abdominal surgery affect stress markers in the lungs and blood. 76 adults were randomly assigned to receive either normal (35%) or high (80%) oxygen during surgery. Researchers measured changes in various biomarkers related to lung injury, inflammation, and blood vessel health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxygen (hyperoxia vs normoxia)

What this could lead to

If it works, this could help guide oxygen use during surgery to reduce stress on the lungs and blood vessels.

What could go wrong

This is a small, completed study that only measured biological markers, not patient outcomes. Results may not change practice without larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istanbul University, Istanbul Faculty of Medicine

    Istanbul, Turkey (Türkiye)