Knee pain relief: which PRP injection works best?

NCT ID NCT04807270

Completed Symptom relief Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different ways of preparing Platelet-Rich Plasma (PRP) injections for people with knee osteoarthritis. 96 participants received three injections over six weeks and were followed for six months. The goal was to see which method better reduces pain, improves function, and enhances quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-Rich Plasma (PRP) injection
What this could lead to: If successful, this could show which PRP preparation method works better for easing knee pain and improving mobility in osteoarthritis.
What could go wrong: This is a small, completed trial with no phase designation, so results may not apply widely. PRP is a common treatment but its effectiveness is still debated.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

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Locations

Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation

Istanbul, Fatıh, 34034, Turkey (Türkiye)

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