Chili pepper cream takes on painkiller gel for jaw pain
NCT ID NCT07598994
First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 3 times
Summary
This study tested whether a cream made from chili pepper extract (capsaicin) or a common pain-relief gel (diclofenac) works better for long-term jaw joint pain. Fifty women with chronic jaw pain applied one of the creams four times a day for a week. Researchers measured pain levels, jaw function, and sensitivity at the start, after one week, and again a month later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Capsaicin 0.075% cream and diclofenac 1% gel
- What this could lead to
- If capsaicin works better, it could offer a new, non-drug option for managing chronic jaw pain.
- What could go wrong
- This is a small, completed trial with only 50 women, so results may not apply to everyone. Capsaicin can cause burning or irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Istanbul University Faculty of Dentistry
Istanbul, Istanbul, 34093, Turkey (Türkiye)
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