Chili pepper cream takes on painkiller gel for jaw pain
NCT ID NCT07598994
First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tested whether a cream made from chili pepper extract (capsaicin) or a common pain-relief gel (diclofenac) works better for long-term jaw joint pain. Fifty women with chronic jaw pain applied one of the creams four times a day for a week. Researchers measured pain levels, jaw function, and sensitivity at the start, after one week, and again a month later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Capsaicin 0.075% cream and diclofenac 1% gel
What this could lead to
If capsaicin works better, it could offer a new, non-drug option for managing chronic jaw pain.
What could go wrong
This is a small, completed trial with only 50 women, so results may not apply to everyone. Capsaicin can cause burning or irritation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Istanbul University Faculty of Dentistry
Istanbul, Istanbul, 34093, Turkey (Türkiye)