PTSD

This study tested whether adding CBD oil to standard therapy helps military veterans with PTSD. Researchers compared therapy plus CBD against therapy plus a placebo in 136 veterans. The goal was to see if CBD helps people process traumatic memories better during therapy, potentia…

This study tested whether adding repeated ketamine infusions to a standard talk therapy (Prolonged Exposure) could help Veterans with PTSD get better faster. 75 participants received either ketamine or a placebo (inactive substance) once a week for three weeks while undergoing th…

This study tested whether adding a specific therapy for psychological trauma (called EMDR) to standard HIV medical care could help people recently diagnosed with HIV. It involved 40 participants who were randomly assigned to receive either standard care alone or standard care plu…

This small pilot study explored whether a non-invasive brain stimulation technique could help veterans with PTSD who weren't improving during the first week of a standard two-week intensive therapy program. Researchers combined the therapy with a procedure called iTBS, which uses…

This small, completed study tested whether combining the drug MDMA with a short course of couples therapy could help veterans with chronic PTSD. Eight veterans and their partners participated. The goal was to see if this approach could safely reduce PTSD symptoms and improve rela…

This study tested whether adding the hormone oxytocin to a proven talk therapy (Prolonged Exposure) could help Veterans with PTSD. The goal was to see if oxytocin helped people stick with the therapy longer and reduced their symptoms more effectively than a placebo. The trial inv…

This study tested whether adding an estrogen pill (estradiol) to a standard talk therapy called Prolonged Exposure could improve treatment results for women with PTSD. Researchers enrolled 83 women and randomly assigned them to receive either the therapy with estrogen or therapy …

This study tested a community program in Kenya designed to help people living with HIV. It combined a savings and loan group with education on parenting, business skills, and mental health therapy. The goal was to see if this support system could help people stick to their HIV me…

This study aimed to find the best score on a short questionnaire to accurately identify people with childbirth-related PTSD. Researchers had 67 people who had given birth fill out the questionnaire and then complete a detailed diagnostic interview. They compared the questionnaire…

This study tested if a single dose of a stress hormone pill (hydrocortisone), taken within 6 hours of a traumatic event, could prevent post-traumatic stress disorder (PTSD). Researchers recruited 201 adults who came to an emergency room after a trauma and were showing high distre…

This study tested whether a non-invasive brain stimulation technique could help veterans with PTSD. Researchers used a powerful magnet to stimulate specific brain areas, comparing it to a sham (fake) treatment. They measured whether it improved PTSD symptoms, depression, and dail…

This study tested if adding a brief writing therapy to a standard 28-day residential addiction program could help Veterans who have both PTSD and a substance use disorder. 56 Veterans were randomly assigned to receive either the standard program alone or the standard program plus…

This study tested whether a 6-week group therapy for PTSD, led by people who have also experienced incarceration and trauma, is helpful for those recently released from prison or jail. 59 participants who had PTSD symptoms joined the therapy groups and completed surveys about the…

This study tested whether a technique using sounds during sleep could make a standard nightmare therapy work better and faster. 46 people with PTSD and frequent nightmares underwent therapy to rewrite their bad dreams. Half also heard a specific sound during their REM sleep, hopi…

This study tested whether a group therapy where teens write about their trauma could help reduce PTSD symptoms. It involved 53 Chinese adolescents with PTSD, comparing those who received the writing therapy to those on a waiting list. Researchers measured PTSD, depression, and an…

This study tested whether a single session of aerobic exercise could help people with PTSD symptoms better control their emotions and focus. Researchers compared 65 women with significant PTSD symptoms who either did 20 minutes of moderate-to-vigorous exercise or sat quietly. The…

This study tested whether it's practical to run a future, larger trial comparing two remote programs for veterans. 42 veterans with PTSD and long-term pain were assigned to either a 12-week Tai Chi class or a general wellness class, both delivered over video. The main goal was to…

This study tested whether a wearable device called Apollo is practical and acceptable for veterans with PTSD. The device delivers gentle vibrations intended to help calm the body's stress response. Researchers measured if veterans would use it and if it affected their heart rate …

This study tested whether virtual reality therapy could prevent anxiety, depression, and PTSD in lung transplant patients recovering in the intensive care unit. Patients on the transplant waiting list used VR headsets to gradually experience simulated ICU sounds and environments,…

This study tested a new Dutch questionnaire designed to measure how people think about traumatic events. Researchers gave the questionnaire to over 500 people, including university students and patients receiving treatment for trauma-related disorders like PTSD. The goal was to s…

This study explored whether the timing of a gentle brain stimulation technique (tDCS) could help people with PTSD better process and reduce fear memories. Researchers worked with 62 adults diagnosed with PTSD, testing stimulation during different phases of a fear-learning task. T…

This study aimed to understand why people with PTSD have a higher risk of heart disease. Researchers measured blood vessel health in 168 adults with a history of trauma, half of whom had PTSD. The goal was to see if specific aspects of PTSD, like fear, are linked to early signs o…

This study aimed to find objective brain-based markers for PTSD, moving beyond reliance on patient interviews and questionnaires. Researchers measured electrical brain activity (EEG) during sleep in veterans with PTSD at different stages of their therapy. The goal was to see if s…