Could a nasal spray of insulin help PTSD?
NCT ID NCT04044534
First seen Jun 26, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study tests whether a daily nasal spray of insulin can reduce PTSD symptoms. Twenty adults with current PTSD will receive either insulin or a placebo for several weeks. Researchers will measure symptom changes using a standard PTSD scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- intranasal insulin
- What this could lead to
- If it works, this could point toward a new way to ease PTSD symptoms using a familiar drug.
- What could go wrong
- This is a very small early-phase trial with only 20 people, so results may not apply widely. Insulin can cause low blood sugar or nasal irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
VA Connecticut Healthcare System
West Haven, Connecticut, 06516, United States
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