PTSD

This study is testing how well a combination of medication and a specific type of talk therapy (cognitive behavioral therapy) helps people with various mental health conditions. It involves 107 adults with diagnoses like anxiety, depression, PTSD, bipolar disorder, or schizophren…

This study is testing whether a one-week virtual therapy program is more effective than a one-week virtual relaxation program at reducing PTSD symptoms. Researchers are enrolling 140 adults with PTSD in Illinois to compare these two approaches. The goal is to understand how these…

This study is testing a therapy that treats PTSD and substance use problems together in teenagers, instead of separately as is usually done. It compares a new family-based therapy to standard treatment to see which works better at reducing substance use and PTSD symptoms over a y…

This study is testing whether a specific type of group therapy, called Cognitive Processing Therapy (CPT), can help reduce symptoms of Post-Traumatic Stress Disorder (PTSD) in incarcerated men and women. About 117 participants are randomly assigned to either receive the therapy s…

This early-stage study is testing the safety and initial effects of a single dose of the medication brexanolone in people who have both PTSD and alcohol use disorder. Researchers want to see if the drug can help reduce drinking triggered by stress. About 25 participants will rece…

This study is testing a 5-week behavioral therapy program designed for women who have experienced a sexual assault in the past year and are struggling with alcohol use. The goal is to see if this combined approach can help reduce symptoms of post-traumatic stress and control prob…

This study is testing whether having a trained service dog helps military veterans with PTSD complete a standard therapy and get better results. Researchers want to see if the dogs help people stick with the treatment, which involves safely confronting traumatic memories. The goa…

This study is testing whether a single dose of MDMA, combined with an intensive two-week therapy program, can help reduce PTSD symptoms. All 40 participants will receive the MDMA-assisted therapy during the treatment. Researchers want to see if adding MDMA makes the established t…

This study is testing a special workshop, led by fellow firefighters, that teaches emotion regulation skills. It aims to prevent PTSD, depression, anxiety, and alcohol use problems in new firefighter recruits. Researchers will compare this workshop to standard mental health educa…

This study is testing whether a brief, three-session therapy can prevent post-traumatic stress disorder (PTSD) in people recovering from spinal cord injuries. Researchers are comparing this special therapy to standard rehabilitation care in 200 patients during their hospital reco…

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' combined with therapy, is safe and helpful for military veterans with PTSD. Fifteen veterans will receive two guided psilocybin sessions along with therapy before and after. Researchers will track…

This study is testing whether gentle electrical stimulation of nerves in the ear or neck can improve sleep quality for veterans with PTSD. Researchers are comparing two different stimulation locations to see which might help people fall asleep faster and stay asleep longer. The s…

This study tests a therapist-assisted self-management program for veterans who have completed trauma-focused therapy for PTSD and shown improvement. The program aims to help veterans maintain their symptom reductions, build confidence in managing symptoms independently, and reduc…

This remote study aimed to provide holistic education and pastoral counseling to help people manage stress and improve wellness in daily life. It was designed for specific unmarried Alaska Medicaid recipients who met religious and lifestyle criteria. The study was withdrawn befor…

This study is testing whether a therapy called Deep Brain Reorienting (DBR) can help reduce symptoms of Post-Traumatic Stress Disorder (PTSD). The therapy involves recalling a traumatic memory while focusing on physical tension in the head and neck, aiming to process the memory i…

This study is testing whether a creative writing group program helps people with serious mental illnesses like schizophrenia, bipolar disorder, or severe depression. About 300 participants will either join the writing groups along with their usual care or continue with usual care…

This study aims to understand how the brain learns fear. Researchers will use virtual reality and safe, mild brain stimulation in 70 people who already have a brain implant for epilepsy. The goal is to map brain and body responses to fear, which could help improve future treatmen…

This study uses brain scans to understand how cannabis affects brain inflammation and function in veterans with PTSD. Up to 100 veterans will receive brain imaging before and after 12 weeks of cannabis treatment to see how their brains change. Researchers hope to link these brain…

This study is investigating whether the time of day a person receives therapy affects how well it works for Post-Traumatic Stress Disorder (PTSD). It involves 52 adults with PTSD who will receive a standard 10-session therapy called Prolonged Exposure, delivered via video call. H…