PTSD
Clinical trials for PTSD explained in plain language.
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VA tests 5-Day brain zap to ease Veterans' PTSD
Disease control Not yet recruitingThis study is testing whether a 5-day intensive brain stimulation treatment can reduce PTSD symptoms in Veterans. Researchers will compare real magnetic stimulation to a placebo treatment in 90 Veterans with PTSD. The goal is to see if this faster approach works as well as tradit…
Matched conditions: PTSD
Phase: PHASE3 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Sleep pill could help veterans overcome trauma fear
Disease control Not yet recruitingThis study is testing whether a common sleep medication (suvorexant) can help veterans with PTSD and insomnia reduce their fear responses. Researchers will use a home-based training program where veterans learn to face fear triggers in a safe way while taking either the medicatio…
Matched conditions: PTSD
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Magic mushroom therapy trial offers hope for Tough-to-Treat PTSD
Disease control Not yet recruitingThis study is testing whether combining a single dose of psilocybin (a compound found in 'magic mushrooms') with an intensive week of therapy can help people with chronic, treatment-resistant PTSD. Fifteen participants will receive the combined treatment and be followed for 12 we…
Matched conditions: PTSD
Phase: PHASE2 • Sponsor: Unity Health Toronto • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New PTSD treatment trial tests neck injection plus therapy
Disease control Not yet recruitingThis study aims to see if combining two treatments works better for reducing PTSD symptoms. One is a standard talk therapy, and the other is a neck injection that calms the body's stress response. Researchers will compare the combination to each treatment alone to see which helps…
Matched conditions: PTSD
Phase: EARLY_PHASE1 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Magic mushroom therapy tested for trauma in women
Disease control Not yet recruitingThis study is testing whether a single dose of psilocybin, taken in a controlled setting with therapy, can help reduce PTSD symptoms in women who have experienced sexual assault. It will involve 35 participants and closely monitor safety, changes in PTSD severity, anxiety, depres…
Matched conditions: PTSD
Phase: PHASE2 • Sponsor: Sunstone Medical • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Simple neck shot tested as new hope for stubborn PTSD
Disease control Not yet recruitingThis study is testing if a simple injection of a sugar-water solution (D5W) into the neck can help people with PTSD that hasn't improved with standard treatments like therapy or medication. It will compare the D5W injection to a placebo injection of saltwater (saline). The goal i…
Matched conditions: PTSD
Phase: PHASE4 • Sponsor: Dr. Dean Reeves Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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New program aims to bridge veterans from initial PTSD care to Gold-Standard treatments
Disease control Not yet recruitingThis study aims to help veterans with PTSD transition from initial stabilization treatments to more effective, recommended therapies. Researchers will interview veterans and clinicians to understand current treatment patterns, then test a new support program designed to facilitat…
Matched conditions: PTSD
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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Magic mushroom therapy tested for Veterans' PTSD
Disease control Not yet recruitingThis study is testing whether psilocybin, the active compound in 'magic mushrooms,' can be safely combined with therapy to help reduce PTSD symptoms. It will involve 150 Georgia military veterans, reservists, or active-duty members with PTSD. Researchers will compare two differen…
Matched conditions: PTSD
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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Could cannabis help veterans face their trauma?
Symptom relief Not yet recruitingThis study is testing whether using cannabis (marijuana) during a specific trauma therapy helps veterans with PTSD. Researchers will give some participants cannabis and others a placebo before therapy sessions to see if it makes the treatment more effective at reducing symptoms l…
Matched conditions: PTSD
Phase: PHASE1 • Sponsor: Wayne State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Smartwatch trial aims to silence nightmares for veterans
Symptom relief Not yet recruitingThis study is testing whether a smartwatch called NightWare can improve sleep for current and former military members who have trouble sleeping, nightmares, PTSD, or a history of brain injury. The watch detects signs of nighttime stress and delivers gentle vibrations to try to ca…
Matched conditions: PTSD
Phase: NA • Sponsor: Uniformed Services University of the Health Sciences • Aim: Symptom relief
Last updated Mar 30, 2026 14:27 UTC
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Military tests phone app to battle insomnia and PTSD
Symptom relief Not yet recruitingThis pilot study is testing whether a self-guided smartphone app can help service members with insomnia sleep better. 144 active-duty military personnel will be randomly assigned to either use the app for five weeks or wait. Researchers will measure changes in sleep quality, dayt…
Matched conditions: PTSD
Phase: NA • Sponsor: Madigan Army Medical Center • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Can movement and touch calm the traumatized brain? new PTSD therapy trial begins
Symptom relief Not yet recruitingThis study is testing whether a body-focused therapy called SMART can help adults with Post-Traumatic Stress Disorder (PTSD). SMART uses movement, touch, and balance exercises to help people feel more connected to their bodies and surroundings. Researchers will enroll 80 adults t…
Matched conditions: PTSD
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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VR headsets could ease pandemic trauma
Symptom relief Not yet recruitingThis study is testing whether virtual reality (VR) therapy can help reduce trauma symptoms related to the COVID-19 pandemic. It will involve 100 healthcare workers and COVID survivors who are experiencing psychological distress. Participants will try five weekly VR sessions desig…
Matched conditions: PTSD
Phase: NA • Sponsor: Soonchunhyang University Hospital • Aim: Symptom relief
Last updated Mar 16, 2026 15:26 UTC
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New program aims to ease mental strain on ICU Patients' families
Symptom relief Not yet recruitingThis study is testing a mental health support program for family members of people who have survived intensive care. The program uses a telehealth platform to help families manage anxiety, depression, and stress. Researchers want to see if this approach is practical and helpful f…
Matched conditions: PTSD
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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Digital coach fights ICU trauma
Symptom relief Not yet recruitingThis study tests whether a digital mental health program helps people recovering from intensive care. 150 patients will either use a special app with coaching and support or receive standard follow-up care. Researchers will compare anxiety, depression, and PTSD symptoms after six…
Matched conditions: PTSD
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Mar 09, 2026 14:26 UTC
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Can a 12-Week wellness plan heal our heroes?
Knowledge-focused Not yet recruitingThis study is looking back at data from a 12-week wellness program designed for veterans and first responders. Researchers will analyze information from about 80 past participants to see if the program helped with anxiety, depression, PTSD, sleep, and overall quality of life. The…
Matched conditions: PTSD
Sponsor: Baylor University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Researchers explore Culturally-Tailored mindfulness to help heal trauma in Justice-Involved black teens
Knowledge-focused Not yet recruitingThis study aims to understand PTSD symptoms and stress in justice-involved Black/African American adolescent girls and their parents. Researchers will interview participants and service providers to adapt a mindfulness-based stress reduction program to better fit their cultural n…
Matched conditions: PTSD
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:09 UTC