Could adderall help PTSD patients connect better?

NCT ID NCT07664631

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial at the University of Chicago tests whether Adderall, a drug used for ADHD, can improve social interactions in people with PTSD. About 40 adults aged 18-65 will receive either Adderall or a placebo and rate their conversations. The goal is to see if this drug offers a new option for the many PTSD patients who don't get better with current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mixed amphetamine salts (Adderall)

What this could lead to

If it works, this could point toward a new way to ease social difficulties in PTSD, offering an alternative for people who don't respond to standard treatments.

What could go wrong

This is a very early Phase 1 trial with only 40 people, so results may not apply widely. Adderall can cause side effects like increased heart rate, anxiety, or insomnia, and may not improve PTSD symptoms overall.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact