METASTATIC COLORECTAL ADENOCARCINOMA

This early-stage study is testing a new oral medication called PF-08032562, both alone and in combination with other cancer drugs, for people with advanced or metastatic breast or colorectal cancer. The main goals are to find a safe dose and see how the body processes the drug. R…

This study is testing whether adding a special radiofrequency device to an existing cancer drug helps people with advanced colorectal cancer that has stopped responding to standard treatments. The device emits specific radio waves, and the drug is called fruquintinib. Researchers…

This early-stage study aims to find the safest and most effective dose of a new two-drug combination for people with advanced colorectal or gastroesophageal (stomach/esophagus) cancers that have spread. The trial will enroll about 45 adults whose cancer has progressed after at le…

This study is for people with colorectal cancer that has spread to up to four other places in the body. It compares the usual approach of chemotherapy drugs alone to a more aggressive strategy that adds targeted treatments to eliminate the visible cancer spots. These added treatm…

This early-stage study is testing whether combining a special low-calorie, plant-based diet with high-dose vitamin C and two immunotherapy drugs is safe and might help control advanced colorectal cancer that has a specific KRAS mutation. The trial will enroll about 15 adults whos…

This early-stage trial is testing the safety and best dose of a new oral drug, CA-4948, when added to a standard chemotherapy regimen for people with advanced colorectal cancer that has spread. The main goal is to see if the combination is safe and tolerable for patients. Researc…

This early-stage study is testing whether adding an experimental drug called ZEN003694 to two existing cancer drugs (cetuximab and encorafenib) is safe and effective for people with advanced colorectal cancer that has stopped responding to previous treatments. The trial will enro…