Could a vitamin b derivative boost chemo for advanced colon cancer?

NCT ID NCT06922383

Recruiting now Disease control Sponsor: Isofol Medical AB Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests a new drug called arfolitixorin for people with metastatic colorectal cancer (cancer that has spread). The drug is a form of vitamin B that may make standard chemotherapy work better. About 90 participants will receive arfolitixorin along with usual chemo drugs, and researchers will compare different doses to find the safest and most effective one. The goal is to see if this new combination can shrink tumors better than current treatments.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm Digestive System Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC COLORECTAL CANCER (MCRC)

Contacts and locations

Locations

Charité - Universitaetsmedizin Berlin
RECRUITING

Berlin, 10117, Germany
Muenchen Klinik gGmbH, Klinik für Onkologie und Hämatologie
NOT_YET_RECRUITING

München, 81737, Germany
Universitaetsklinikum Essen AöR, Department of Medical Oncology
NOT_YET_RECRUITING

Essen, 45147, Germany

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