Could a vitamin b derivative boost chemo for advanced colon cancer?

NCT ID NCT06922383

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests a new drug called arfolitixorin for people with metastatic colorectal cancer (cancer that has spread). The drug is a form of vitamin B that may make standard chemotherapy work better. About 90 participants will receive arfolitixorin along with usual chemo drugs, and researchers will compare different doses to find the safest and most effective one. The goal is to see if this new combination can shrink tumors better than current treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm Digestive System Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité - Universitaetsmedizin Berlin

    RECRUITING

    Berlin, 10117, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Muenchen Klinik gGmbH, Klinik für Onkologie und Hämatologie

    NOT_YET_RECRUITING

    München, 81737, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaetsklinikum Essen AöR, Department of Medical Oncology

    NOT_YET_RECRUITING

    Essen, 45147, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••