Can a Drug-Radiation combo outsmart Treatment-Resistant colorectal cancer?
NCT ID NCT07720115
First seen Jul 22, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This phase 2 trial is testing whether combining an experimental drug called S-531011 with a precise radiation technique known as RadScopal can help control metastatic colorectal cancer that has not responded to prior treatments. The study enrolls about 30 adults with advanced disease who have already received standard chemotherapy. Researchers are primarily looking at safety and how well the combination works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental drug called S-531011 plus a special radiation technique called RadScopal
- What this could lead to
- If it works, this combination could offer a new treatment option for people with metastatic colorectal cancer that has stopped responding to standard chemotherapy.
- What could go wrong
- This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The drug is experimental, and side effects are not yet fully known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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