METASTATIC COLORECTAL ADENOCARCINOMA
Clinical trials for METASTATIC COLORECTAL ADENOCARCINOMA explained in plain language.
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Can two immune boosters outsmart Chemo-Resistant colon cancer?
Disease control Not yet recruitingThis phase 3 trial is testing whether adding two immune-boosting drugs, iparomlimab and tuvonralimab, to standard chemotherapy can help people with a specific type of metastatic colorectal cancer that has stopped responding to first-line treatment. The study includes about 270 ad…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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Can a Drug-Radiation combo outsmart Treatment-Resistant colorectal cancer?
Disease control Not yet recruitingThis phase 2 trial is testing whether combining an experimental drug called S-531011 with a precise radiation technique known as RadScopal can help control metastatic colorectal cancer that has not responded to prior treatments. The study enrolls about 30 adults with advanced dis…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Can a four-drug cocktail shrink hard-to-treat colorectal cancer?
Disease control Not yet recruitingThis phase 2 trial is testing whether adding two extra drugs—bevacizumab and sintilimab—to the usual combination of irinotecan and cetuximab can shrink tumors in people with advanced colorectal cancer that no longer responds to irinotecan. The study enrolls 160 adults with RAS wi…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Experimental drug SHR-A1904 takes on Hard-to-Treat colorectal cancer
Disease control Not yet recruitingThis phase 2 trial tests an experimental drug called SHR-A1904 in people with advanced colorectal cancer that has spread and no longer responds to standard treatments. The study aims to see if the drug is safe and can shrink tumors or slow the disease. Participants must have alre…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Could a diabetes drug boost chemo for tough cancers?
Disease control Not yet recruitingThis early-phase trial will test whether adding semaglutide (a GLP-1 drug used for diabetes and weight loss) to standard chemotherapy is safe and tolerable for people with metastatic pancreatic, colorectal, or liver cancer. About 30 participants will receive weekly semaglutide in…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: University of Arizona • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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New combo therapy targets Hard-to-Treat cancers
Disease control Not yet recruitingThis early-phase study tests a new drug combination (L19IL2 plus ruxolitinib) in people with advanced kidney, pancreatic, or colorectal cancers that have stopped responding to standard treatments. The main goals are to find a safe dose and check for side effects. About 96 partici…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Philogen S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New combo therapy aims to fight advanced colorectal cancer
Disease control Not yet recruitingThis phase II trial tests whether a special radiotherapy regimen followed by targeted therapy and immunotherapy can shrink tumors in people with advanced colorectal cancer that has not responded to prior treatments. About 33 participants will receive the treatment and be monitore…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New hope for advanced colon cancer: drug duo targets tumors
Disease control Not yet recruitingThis study tests a new drug combination (SHR-1811 plus bevacizumab) as a second-line treatment for people with metastatic colorectal cancer that has worsened after initial therapy. About 80 adults aged 18-75 will participate. The goal is to see if the combo shrinks tumors and del…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New drug combo aims to fight colorectal cancer when standard chemo fails
Disease control Not yet recruitingThis Phase 2 trial tests whether a new drug combination (fruquintinib plus trifluridine/tipiracil) works better than a standard combo (bevacizumab plus trifluridine/tipiracil) for people with advanced colorectal cancer that has not responded to standard chemotherapy. About 292 ad…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC