METASTATIC COLORECTAL ADENOCARCINOMA
Clinical trials for METASTATIC COLORECTAL ADENOCARCINOMA explained in plain language.
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New hope for tough-to-treat colon cancer? drug cocktail enters human trials
Disease control OngoingThis early-stage trial tests a combination of chemotherapy (FOLFOX), a blood-vessel blocker (bevacizumab), and two immunotherapy drugs (botensilimab and balstilimab) in 20 people with a type of advanced colorectal cancer called MSS that has spread. The goal is to see if this mix …
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 03:13 UTC
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New drug cocktail shows promise for Hard-to-Treat colorectal cancer
Disease control OngoingThis study tests a combination of three drugs (botensilimab, balstilimab, and regorafenib) in people with a type of advanced colorectal cancer that has not responded to prior chemotherapy. The goal is to see if this mix can shrink tumors or slow the cancer's growth. About 28 adul…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 03:08 UTC
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New hope for stubborn colon cancer: three-drug combo enters early testing
Disease control TerminatedThis early-phase study tests whether adding an experimental drug (ZEN003694) to two approved cancer drugs (cetuximab and encorafenib) is safe and effective for people with a specific type of advanced colorectal cancer (BRAF V600E) that has spread and no longer responds to standar…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for advanced colon cancer patients who stopped responding to standard treatments
Disease control OngoingThis study tests two drugs, panitumumab and trametinib, in 59 people with stage IV colorectal cancer that no longer responds to standard therapies. Panitumumab helps the immune system attack cancer cells, while trametinib blocks enzymes that help tumors grow. The goal is to see i…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New hope for Tough-to-Treat colorectal cancer: immunotherapy combo under trial
Disease control OngoingThis study tests whether a combination of immunotherapy (atezolizumab) plus chemotherapy and a targeted drug works better than immunotherapy alone for people with a specific genetic type of advanced colorectal cancer (dMMR/MSI-H). About 120 adults whose cancer has spread will be …
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:44 UTC
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Poop pills plus immunotherapy: new hope for colorectal cancer patients?
Disease control OngoingThis study tests whether a fecal microbiota transplant (FMT) — transferring healthy bacteria from stool — can help the immune drug pembrolizumab or nivolumab work better in people with advanced colorectal cancer who didn't respond to immunotherapy before. About 15 adults with a s…
Matched conditions: METASTATIC COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:13 UTC