New combo treatment may slow colorectal cancer spread

NCT ID NCT05862051

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This trial is for people with colorectal cancer that has spread to a few spots in the body but cannot be fully removed by surgery alone. After 3-4 months of standard chemotherapy, participants either continue chemotherapy alone or also receive local ablative therapy—such as surgery, radiation, or heat/cold ablation—to target remaining tumors. The goal is to see if adding this local treatment helps delay the cancer from growing further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Local ablative therapy (surgery, radiation, or heat/cold ablation)

What this could lead to

If successful, this approach could extend the time before colorectal cancer worsens, offering a new way to manage the disease.

What could go wrong

This is a very small early-phase trial with only 6 participants, so results may not apply broadly. The added procedures also carry risks like infection or side effects from radiation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barwon Health

    Geelong, Victoria, 3220, Australia

  • Bendigo Hospital

    Bendigo, Victoria, 3550, Australia

  • Border Medical Oncology

    Albury, New South Wales, 2640, Australia

  • Eastern Health

    Box Hill, Victoria, 3128, Australia

  • Northeast Health Wangaratta

    Wangaratta, Victoria, 3677, Australia

  • Peter MaCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • St Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

  • The Northern Hospital

    Epping, Victoria, 3076, Australia

  • Western Health

    Saint Albans, Victoria, 3021, Australia