Poop pills plus immunotherapy: new hope for Hard-to-Treat colorectal cancer?
NCT ID NCT04729322
First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 31 times
Summary
This study tests whether a fecal microbiota transplant (transferring healthy bacteria from stool) can help the immune system respond to anti-PD-1 drugs like pembrolizumab or nivolumab in people with advanced colorectal cancer who previously did not respond to these immunotherapies. About 15 adults with metastatic mismatch repair-deficient colorectal or small intestinal cancer will receive the transplant along with re-introduced immunotherapy. The goal is to see if this combination can shrink tumors and control the disease.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC COLORECTAL ADENOCARCINOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.