Poop pills plus immunotherapy: new hope for Hard-to-Treat colorectal cancer?
NCT ID NCT04729322
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times
Summary
This study tests whether giving a fecal microbiota transplant (healthy bacteria from stool) along with re-starting immunotherapy (pembrolizumab or nivolumab) can help shrink tumors in people with advanced colorectal cancer that did not respond to immunotherapy alone. The trial includes 15 adults with mismatch repair-deficient (dMMR) metastatic colorectal or small intestinal cancer. The goal is to see if changing the gut bacteria can make the immune therapy work better.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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