New hope for Tough-to-Treat colorectal cancer?

NCT ID NCT05990543

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new drug called nelmastobart combined with the chemotherapy capecitabine in people with metastatic colorectal cancer that no longer responds to standard treatments. About 59 adults will receive the combination to see if it is safe and can slow cancer growth. The goal is to find a better option for patients with limited choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nelmastobart and capecitabine

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced colorectal cancer who have run out of standard chemotherapy choices.

What could go wrong

This is an early-phase trial with only 59 participants, so results may not apply to all patients. The drug combination may cause side effects or fail to improve survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Korea University Medical Center 73, Goryeodae-ro, Seongbuk-gu

    Seoul, Seoul, 02841, South Korea