New combo therapy aims to fight advanced colorectal cancer
NCT ID NCT07467590
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial tests whether a special radiotherapy regimen followed by targeted therapy and immunotherapy can shrink tumors in people with advanced colorectal cancer that has not responded to prior treatments. About 33 participants will receive the treatment and be monitored for tumor response and survival. The study is not yet recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- High- and low-dose radiotherapy followed by anti-angiogenic tyrosine kinase inhibitor (TKI) and anti-PD-1 antibody therapy
- What this could lead to
- If this works, it could offer a new treatment option for people with advanced colorectal cancer that has not responded to other therapies.
- What could go wrong
- This is a small, early-phase trial with only 33 participants, so results may not apply to everyone. The combination of treatments may cause side effects, and it is not yet known if it will improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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