Can lower chemo doses help older cancer patients?

NCT ID NCT06840977

Recruiting now Knowledge-focused Sponsor: Matteo Clavarezza Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study looks at medical records of 51 patients aged 70 and older with metastatic colorectal cancer. Researchers want to see if using lower doses of chemotherapy along with full-dose targeted therapy can reduce serious side effects like low white blood cell counts and severe diarrhea. The goal is to find a safer treatment option for older adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose safer, more effective chemotherapy doses for elderly patients with metastatic colorectal cancer.
What could go wrong: This is a small, retrospective study that only looks back at past cases, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colonic neoplasm colorectal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLON ADENOCARCINOMA

Contacts and locations

Locations

E.O. Ospedali Galliera
RECRUITING

Genova, GE, 16128, Italy
E.O. Ospedali Galliera
NOT_YET_RECRUITING

Genoa, Liguria, 16128, Italy

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