IRRITABLE BOWEL SYNDROME

This study tested whether adding probiotic supplements to the standard antibiotic (rifaximin) could better control SIBO symptoms like bloating and constipation. 129 adults with SIBO took either probiotics or a placebo alongside their antibiotic for 14 days. The goal was to see if…

This study tested whether a home-based audio program of gut-directed hypnotherapy could improve sleep and reduce belly pain in children aged 8-18 with irritable bowel syndrome or similar gut-brain disorders. 46 children participated, with one group using the audios for 6 weeks wh…

This study looked at whether indoor physical activity can improve symptoms and gut health in people with both fibromyalgia and irritable bowel syndrome (IBS). 165 adults with these conditions took part. The goal was to see if exercise reduces pain, fatigue, and digestive issues, …

This study tested three different eating plans in 135 adults with irritable bowel syndrome with diarrhea (IBS-D) to see which best reduces stomach pain, bloating, and other symptoms. Participants followed either a low-FODMAP diet, a Tritordeum-based diet (a special type of wheat)…

This study looked at whether reducing FODMAPs—certain carbohydrates found in many foods—can ease persistent stomach symptoms in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then randomly assigned 80 adults to test a low FODMAP …

This study tested a non-instrumental biofeedback technique to help people with abdominal bloating caused by Irritable Bowel Syndrome (IBS) or dyspepsia. 41 participants were taught exercises to control their belly and chest muscles using a video, or received a placebo. The goal w…

This study looked at whether a simple breath test can help identify which people with diarrhea-predominant irritable bowel syndrome (IBS-D) are more likely to get relief from the antibiotic rifaximin. 148 adults with IBS-D took the breath test and then received rifaximin treatmen…

This study tested a non-invasive treatment called rTMS (repeated transcranial magnetic stimulation) for chronic belly pain in 42 adults with irritable bowel syndrome with diarrhea (IBS-D). Researchers used brain scans to find overactive pain areas and then applied magnetic pulses…

This small pilot study tested whether varenicline, a drug typically used to help people quit smoking, could change how the rectum senses pressure in people with irritable bowel syndrome (IBS) and chronic belly pain. Eight adults with IBS (but not constipation type) took part. The…

This study tested whether an online service that provides personalized low-FODMAP menus and nutritional support can improve quality of life and control symptoms in people with irritable bowel syndrome (IBS). Forty adults with IBS followed the diet using a web platform for six mon…

This study tested a daily synbiotic supplement (a mix of probiotics and prebiotics) in 48 adults with irritable bowel syndrome (IBS) to see if it is safe and helps with symptoms. Participants took either the supplement or a placebo for 12 weeks. The main goal was to check for sid…

This study looked at whether a diet low in FODMAPs (certain carbohydrates) can ease symptoms of Irritable Bowel Syndrome (IBS). Researchers tested 112 adults with IBS to see if a fructose breath test could predict who would benefit from the diet. The goal was to find a simple way…

This study tested whether a standardized Boswellia extract (a herbal supplement) combined with structured education sessions could improve symptoms of irritable bowel syndrome (IBS) in 60 adults aged 18-39. Participants took 500 mg of the extract twice daily for 30 days and atten…

This study tested whether ethosuximide, a drug usually used for seizures, can reduce belly pain in people with irritable bowel syndrome (IBS). About 162 adults with IBS and moderate-to-severe pain took part. The goal was to see if the drug lowers pain and improves quality of life…

This study tested whether a smartphone app called Zemedy can improve quality of life for adults with Irritable Bowel Syndrome (IBS). 453 people with IBS used either Zemedy or a relaxation training app. The goal was to see if the app helps reduce symptoms and improve daily life.

This study tested three approaches to treat vestibulodynia, a long-term vulvar pain condition that affects about 1 in 6 women. 209 women received either a numbing cream, an oral medication, both, or a placebo to see which worked best for pain relief. The goal was to help women an…

This small pilot study tested a non-invasive device that gently stimulates the vagus nerve through the skin. Ten women with Irritable Bowel Syndrome (IBS) used the device daily for six months. The goal was to see if it could improve digestive symptoms, reduce inflammation, and en…

This study tested a new diet called the 5Ad diet against the well-known low FODMAP diet in 52 adults with ongoing gut issues like bloating, pain, and irregular bowel habits. Each person tried both diets for 7 days, with a break in between. The goal was to see if the 5Ad diet work…

This study looked at whether insomnia affects pain sensitivity in people with Irritable Bowel Syndrome (IBS). Researchers measured pain thresholds in 70 participants, including IBS patients with and without insomnia, healthy volunteers, and people with insomnia alone. The goal wa…

This study looked at whether gluten or whole wheat (which contains gluten plus other proteins) causes stomach and bowel symptoms in people with Irritable Bowel Syndrome (IBS). 29 adults who already felt better on a gluten-free diet were given special bars containing either purifi…

This study looked at whether IBS symptoms come back depending on the dose of certain FODMAPs (mannitol and fructans) after a successful low-FODMAP diet. 45 adults with IBS took part in a blinded test where they received increasing doses of these FODMAPs to find the amount that tr…

This study looked at how FODMAPs (certain carbohydrates that can cause gas and bloating) directly affect movement in the large intestine. Fifteen healthy volunteers each had three colonoscopies to measure colon pressure and receive FODMAP infusions. The goal was to understand the…

This study looked at why certain foods cause symptoms in people with irritable bowel syndrome (IBS). Researchers focused on how gut bacteria produce histamine when digesting specific carbohydrates (FODMAPs). Thirty adults with IBS followed a low-FODMAP diet and took special drink…

This study looked at 163 children aged 7-12 with chronic belly pain (like irritable bowel syndrome) to see if simple tests could predict whether they would benefit more from cognitive behavioral therapy (CBT) or a low FODMAP diet. The goal was to personalize treatment and avoid t…