IRRITABLE BOWEL SYNDROME
Clinical trials for IRRITABLE BOWEL SYNDROME explained in plain language.
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Simple breath test could predict best IBS treatment
Disease control CompletedThis study aimed to see if a simple breath test could help doctors predict which patients with diarrhea-predominant Irritable Bowel Syndrome (IBS-D) would respond well to the antibiotic rifaximin. About 148 adults with IBS-D took the breath test, received a 14-day course of rifax…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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Can friendly bacteria boost gut treatment? study investigates
Disease control CompletedThis study tested whether adding probiotic supplements to standard antibiotic treatment helps people with small intestinal bacterial overgrowth (SIBO). 129 participants with SIBO received a 14-day antibiotic course. Half also took probiotics, while the other half took a placebo (…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Pomeranian Medical University Szczecin • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Scientists test personalized pain relief for millions of women
Disease control CompletedThis study tested different treatments for vestibulodynia, a common chronic pain condition affecting the vulva. Researchers compared a numbing cream, an antidepressant pill, a combination of both, and a placebo to see which best reduced pain and improved quality of life. They als…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: PHASE2 • Sponsor: Duke University • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Scientists pinpoint exact food amounts that trigger IBS Flare-Ups
Symptom relief CompletedThis study aimed to help people with Irritable Bowel Syndrome (IBS) figure out exactly how much of certain hard-to-digest foods they can eat without their symptoms coming back. After participants successfully followed a strict low-FODMAP diet to calm their symptoms, researchers g…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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New Mind-Body technique shows promise for taming tummy troubles
Symptom relief CompletedThis study tested a simple, non-instrumental biofeedback technique to help people reduce visible abdominal bloating that occurs after eating. 41 participants with conditions like irritable bowel syndrome were taught specific breathing and posture exercises to perform before and a…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Could a Quit-Smoking pill soothe your gut pain?
Symptom relief CompletedThis small, early-stage study from the Mayo Clinic explored whether varenicline, a medication used to help people quit smoking, could reduce abdominal pain and sensitivity in people with irritable bowel syndrome (IBS). Eight adults with IBS-related pain participated. Researchers …
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Magnetic pulses to the brain tested for easing IBS pain
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique could reduce chronic gut pain in people with a specific type of Irritable Bowel Syndrome (IBS-D). 42 participants were randomly assigned to receive either the real magnetic stimulation or a sham (fake) treatment…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Could a gentle ear zap ease IBS pain? early study investigates
Symptom relief CompletedThis small, completed pilot study explored whether a non-invasive electrical stimulation device, placed on the ear to target the vagus nerve, could improve symptoms and quality of life for women with Irritable Bowel Syndrome (IBS). The study followed 10 women for 6 months to see …
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Can a simple diet change tame your IBS?
Symptom relief CompletedThis study tested whether a low FODMAP diet helps reduce symptoms of Irritable Bowel Syndrome (IBS). Researchers also checked if a simple breath test could predict which patients would benefit most from this diet. The goal was to see if dietary changes could provide relief for pe…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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New Gut-Friendly diet challenges standard IBS treatment
Symptom relief CompletedThis study tested whether a new diet called the 5Ad diet works as well as the commonly used low FODMAP diet for reducing symptoms of irritable bowel syndrome (IBS) and similar gut disorders. Fifty-two adults with chronic digestive symptoms tried each diet for one week, with a bre…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: University of Suffolk • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Can a gym routine soothe chronic pain and gut problems?
Symptom relief CompletedThis study tested whether a supervised, indoor exercise program could improve symptoms for people with fibromyalgia and irritable bowel syndrome (IBS). For four months, 165 adult participants followed a twice-weekly gym routine of aerobic, strength, and flexibility exercises. Res…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Scientists test 24-Strain 'Gut Bug' cocktail for IBS relief
Symptom relief CompletedThis study tested whether a daily mix of 24 beneficial bacteria and fibers (a synbiotic) is safe and can help people with irritable bowel syndrome (IBS). For 12 weeks, 48 adults with IBS took either the synbiotic or a placebo pill. Researchers closely monitored safety and used ad…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: PHASE2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Can listening to hypnosis tapes ease Kids' tummy troubles and improve sleep?
Symptom relief CompletedThis study tested whether a 6-week audio program of gut-directed hypnotherapy, done at home, could help children with chronic stomach pain conditions like IBS. Researchers wanted to see if this approach was practical for families and if it could improve sleep quality and reduce p…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Children's Hospital at Montefiore • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Can a custom online diet plan tame your IBS?
Symptom relief CompletedThis study tested whether an online service that provides personalized low-FODMAP diet menus and nutritional support could improve quality of life and symptoms for people with irritable bowel syndrome (IBS). Forty French-speaking IBS patients used the web-based platform to follow…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC
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Can a phone app ease your IBS? new study investigates
Symptom relief CompletedThis study tested whether a new self-help app called Zemedy is an acceptable and helpful tool for people with Irritable Bowel Syndrome (IBS). Researchers compared it to a different app focused on education and relaxation training. The goal was to see if using the Zemedy app could…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Feb 19, 2026 14:38 UTC
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Could better sleep ease IBS pain? new study investigates
Knowledge-focused CompletedThis study aimed to understand if sleep problems like insomnia are linked to increased gut pain sensitivity in people with Irritable Bowel Syndrome (IBS). Researchers compared pain thresholds in four groups: healthy people, people with only insomnia, people with only IBS, and peo…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists hunt for clues to match kids with best stomach pain therapy
Knowledge-focused CompletedThis study aimed to find out if simple body measurements could predict which of two common treatments would work better for children with chronic stomach pain. Researchers tested 163 children aged 7-12 to see if their heart rate, gut bacteria, or other body signals could show whe…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists probe Gut's reaction to problem foods
Knowledge-focused CompletedThis study aims to understand how certain hard-to-digest foods (FODMAPs) directly affect the colon's movements and cause symptoms in people with Irritable Bowel Syndrome (IBS). Researchers placed a measuring tube in the colons of 15 healthy volunteers during three separate proced…
Matched conditions: IRRITABLE BOWEL SYNDROME
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC