Can enzyme pills beat the bloat? new study tests a simple fix for IBS sufferers

NCT ID NCT07465562

Completed Symptom relief Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study tested whether a dietary supplement containing digestive enzymes (Galactol®) could reduce bloating after meals in people with irritable bowel syndrome (IBS). 300 adults were randomly assigned to take the enzyme supplement plus a low-FODMAP diet, or just the diet alone, for 14 days. The main goal was to see if bloating intensity improved more with the supplement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: digestive enzyme supplement (alpha-galactosidase, beta-galactosidase, prolyl-endopeptidase)
What this could lead to: If it works, this could offer a simple, over-the-counter option to ease bloating after meals for people with IBS.
What could go wrong: This is a small, short-term study (14 days) with no blinding, so results may be influenced by placebo effects. The supplement is tested alongside a special diet, so it's unclear if the supplement alone would help.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL BLOATING IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

Casa di cura Quisisana

Rome, Lazio, 00197, Italy
Nutribol

Reggio Calabria, Calabria, 89124, Italy

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