App-Based therapy shows promise for IBS relief

NCT ID NCT04665271

Completed Symptom relief Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a smartphone app called Zemedy, which delivers cognitive-behavioral therapy, can improve quality of life and reduce symptoms in adults with Irritable Bowel Syndrome (IBS). Over 450 participants used either Zemedy or a relaxation training app for comparison. The goal was to see if a digital, self-guided therapy is an acceptable and effective way to manage IBS.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Zemedy app (digital cognitive-behavioral therapy)
What this could lead to: If it works, this could offer a convenient, app-based way to manage IBS symptoms and improve quality of life without medication.
What could go wrong: This is a completed trial comparing two apps, not a new drug. Results may show only modest benefits, and the app may not work for everyone with IBS.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, 19104-6018, United States

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