App-Based therapy shows promise for IBS relief
NCT ID NCT04665271
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a smartphone app called Zemedy, which delivers cognitive-behavioral therapy, can improve quality of life and reduce symptoms in adults with Irritable Bowel Syndrome (IBS). Over 450 participants used either Zemedy or a relaxation training app for comparison. The goal was to see if a digital, self-guided therapy is an acceptable and effective way to manage IBS.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Zemedy app (digital cognitive-behavioral therapy)
What this could lead to
If it works, this could offer a convenient, app-based way to manage IBS symptoms and improve quality of life without medication.
What could go wrong
This is a completed trial comparing two apps, not a new drug. Results may show only modest benefits, and the app may not work for everyone with IBS.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104-6018, United States