Could a seizure drug soothe IBS belly pain?
NCT ID NCT02973542
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether ethosuximide, a drug used for epilepsy, can reduce belly pain in people with irritable bowel syndrome (IBS). 162 adults with IBS took either the drug or a placebo. The goal was to see if the drug could lower pain and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ethosuximide
- What this could lead to
- If it works, this could point toward a new treatment option for abdominal pain in irritable bowel syndrome.
- What could go wrong
- This is a phase 2 trial, so results are still early. The drug may not prove effective or may cause side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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Other studies related to the condition(s) this trial covers.
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