HEALTHY VOLUNTEERS

This study is checking the safety of the MenQuadfi® vaccine, which protects against four types of meningococcal disease. About 706 healthy people aged 6 weeks to 55 years in South Korea will be watched for side effects after getting the vaccine in regular clinics. The goal is to …

This study is checking the safety of a high-dose flu vaccine (Efluelda) in adults aged 65 and older in South Korea. About 670 participants will receive one shot and be monitored for side effects over about a month. The goal is to confirm the vaccine is safe when used in everyday …

This first-in-human study will test a new radioactive imaging agent called MeFAMP to see if it can safely and accurately detect brain tumors using PET scans. The study includes 28 people: healthy volunteers and patients with recurrent high-grade glioma or brain metastases from ot…

This study aims to prevent obesity in teens and young adults (ages 18-25) who are at high risk due to family history and higher body weight. Researchers will test a program that combines lifestyle coaching with medication to target the biological causes of unhealthy weight gain. …

This study tests whether a single dose of an experimental drug called (2R,6R)-HNK can reduce short-term pain in healthy adults without the addictive side effects of opioids. Up to 92 volunteers aged 18-60 will receive either HNK, a placebo, or no treatment, and will undergo pain …

This early-stage study will test how two different liquid forms of metformin affect blood sugar compared to regular metformin tablets. Twenty-four healthy adults will take short-term doses and have their blood glucose measured. The goal is to see if the liquid versions work diffe…

This study looks at how brief periods of low oxygen (intermittent hypoxia) affect a measure called 'loop gain,' which reflects how your body controls breathing. Researchers want to understand if these oxygen dips can make breathing control less stable, which may help explain slee…

This study looks at how the body handles the experimental drug BGB-58067 when taken with two common medicines that change liver enzyme activity. Thirty healthy adults will take BGB-58067 with either phenytoin (an enzyme booster) or itraconazole (an enzyme blocker). The goal is to…

This study uses focused ultrasound to gently stimulate parts of the brain responsible for vision and hearing in 20 healthy adults aged 21-55. The goal is to find the best ultrasound settings to reliably produce visual flashes or sounds, which will help improve future treatments f…

This early-stage study tests whether liquid metformin causes fewer stomach issues than standard tablets. Twenty-four healthy adults will try single doses of two liquid strengths and one tablet, then report side effects. The goal is to find a more tolerable form of this common dia…

This study tests whether doing sit-to-stand exercises with a blood flow restriction cuff on the legs can improve back muscle endurance and balance better than the same exercises without the cuff. Researchers will study 70 healthy adults aged 20-25 over 6 weeks. The goal is to see…

This early-stage study tests an oral drug called ISM4808 in 86 healthy adults in China. The main goal is to see if the drug is safe and how the body processes it. Participants will receive either the drug or a placebo, and researchers will monitor for side effects. This study doe…

This study looks at how the design of breathing masks affects breathing in 10 healthy volunteers. Participants will try four different masks while using a breathing machine. The goal is to see if mask design changes breathing patterns, carbon dioxide levels, and breathing rate. T…

This early-stage study tests the safety and tolerability of KMY tablets in 120 healthy adults aged 18 to 45. Participants receive either the drug or a placebo, and researchers monitor side effects, how the drug moves through the body, and whether food affects its absorption. The …

This study looks at whether Kinesio Taping can immediately improve hand and arm performance in healthy adults. 36 participants will be randomly assigned to get real tape, fake tape, or no tape, then do hand strength and typing tests. The goal is to see if any improvements come fr…

This early-stage study tests the safety and tolerability of a new drug called migaldendranib in 36 healthy volunteers. Participants receive weekly injections, and researchers monitor for side effects and how the drug moves through the body. The study does not aim to treat any dis…

This early-stage study tests a new drug called BMS-986533 in 118 healthy adults to see if it's safe and how the body processes it. Researchers will also check if food or stomach acid changes how the drug works, and if it interacts with other medications. Participants will not rec…

This study aims to see if a simple, markerless motion capture system using only 4 cameras can accurately measure how children walk. Researchers will study 125 healthy volunteers aged 6 to 17. If successful, this could make gait analysis easier and more widely available for childr…

This early-stage trial tests the safety and how the body processes VV913 capsules in 24 healthy Chinese men aged 18-45. Participants receive multiple doses to check for side effects and measure drug levels in the blood. The study is not intended to treat any disease but to gather…

This study tests whether a supplement called TRPTI (oleoylethanolamide) can improve gut health and metabolism in healthy adults. Researchers will measure changes in blood markers and gut bacteria over 8 weeks. 90 healthy adults aged 18+ with a BMI between 18.5 and 29.9 will take …

This study looks at how different phases of the menstrual cycle relate to muscle strength and physical performance in active women aged 18-35. Participants will track their cycle with a mobile app and attend three lab visits for non-invasive tests like strength and body compositi…

This study looks at how two types of fasting—Ramadan dry fasting (no food or water from dawn to sunset) and standard 16:8 time-restricted feeding (water allowed)—affect the body's ability to clean out and renew mitochondria, the energy centers of cells. Researchers will measure b…

This study tests a new set of audio exercises called SOMA, designed to make mindfulness research more accurate and inclusive. Researchers want to see if these exercises can truly measure mindfulness without bias, especially for people without a university degree. 360 healthy adul…

This early-stage study looks at how eating a high-fat or standard meal changes the way the body absorbs a single dose of VV913. It involves 12 healthy Chinese men aged 18-45. The goal is to gather safety and drug-level information, not to treat any disease.

This study compares 69 healthy volunteers to people with idiopathic environmental intolerance (IEI), a condition where patients experience symptoms like pain, fatigue, or dizziness from everyday exposures (e.g., chemicals, Wi-Fi) with no clear physical cause. Researchers will use…

This study checks if two different versions of a drug (IN-M00007 and IN-R00007) are absorbed and processed the same way in the body. It involves 60 healthy adults aged 19 to 59 who will take a single dose of each drug at different times. The goal is to see if they are equivalent …

This early-stage study looks at how Hezkue® oral sildenafil suspension behaves in the body after moderate alcohol consumption. Twenty-four healthy adults will take the medication under controlled conditions, and researchers will measure drug levels and how quickly it works. The g…

This study looks at how stimulating a nerve in the ear with different frequencies changes heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Each person will try five different stimulation settings (including a sham) in separate sessions. The goal is to un…

This study looks at how different durations of a gentle, non-invasive ear stimulation (called taVNS) affect heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Participants will receive either real or sham stimulation for 5, 10, or 15 minutes on separate vi…

This study looks at whether the hormone progesterone changes how muscles build protein after resistance exercise. Twenty healthy women aged 18-30 will take either progesterone pills or a placebo, then do leg exercises. Researchers will measure muscle growth using biopsies and blo…

This early-stage study tests whether a new formulation of the antibiotic polymyxin B (VRP-034) is safer for the kidneys than the current version. About 48 healthy adult men will receive either the new or standard drug, and researchers will measure kidney injury markers in urine. …

This study explores whether real-time brain scans (fMRI) can help healthy people change how they perceive social situations. Ten volunteers will undergo six MRI sessions while watching animations and receiving feedback on their brain activity. The goal is to understand the brain'…

This early-stage study tests a new type of brain stimulation called high-density theta burst stimulation (hdTBS) in 35 healthy adults aged 22 to 60. The goal is to check if it is safe and to see how it affects the brain compared to standard stimulation. Participants will have fou…

This early-stage study tests the safety of a new drug called HS-20152 in 32 healthy adults aged 18 to 64. The drug targets the complement system, part of the body's immune response. Researchers will monitor for side effects and measure how the drug moves through the body. This st…

This early-stage study looks at how food and ethnic background affect the way a new drug, JPI-547, moves through the body. It involves 36 healthy men of Korean, Caucasian, or Chinese descent who take a single dose. The goal is to gather safety and drug-level data, not to treat an…

This study looks at how stimulating the vagus nerve at different frequencies changes heart rate, blood pressure, and breathing in healthy adults aged 18-30. Each person will try five different stimulation settings (including a sham/placebo) in random order. The goal is to find wh…

This early-stage study tests a single dose of the drug BMS-986435 in 24 people with normal liver function or mild-to-moderate liver impairment. The goal is to see how the liver affects drug levels in the blood and check for side effects. Participants must have healthy hearts and …

This study looks at how a new tablet form of the drug sonrotoclax is absorbed by the body, and whether food changes that. It involves 12 healthy adults who will take the drug once under different conditions. The results will help guide future dosing recommendations.

This study tests a new computer method (HDC) to recognize hand gestures using muscle sensors on the forearm. Ten healthy volunteers will perform gestures while wearing a sensor armband. The goal is to see if the new method is more accurate than standard approaches. This is a tech…

This study looks at how long heart rate recordings should be to best detect changes from a mild nerve stimulation in the ear. Forty healthy adults will receive both real and fake stimulation in random order. Researchers will compare 1-minute, 5-minute, and 10-minute recordings to…

This study looks at how a targeted nerve block near the wrist affects blood flow in healthy volunteers. Twenty people will have their hand blood flow and temperature measured before and after the block, using sensors and thermal cameras. The goal is to understand the body's autom…

This study looks at whether a single dose of nicotinamide riboside (NR), a common supplement, can change sleep patterns in healthy adults who have mild sleep troubles. Twenty volunteers will have their sleep measured overnight with advanced monitoring after taking either NR or a …

This study looks at how a dairy drink with extra protein, calcium, and vitamin D affects physically active adults aged 18 to 39. Over 8 weeks, 50 volunteers will drink the product and take tests on strength, body composition, and how they feel. The goal is to see if the drink hel…

This study looks at how different vibration frequencies from a smartphone app affect hand performance in healthy young adults. Twenty participants will test three vibration levels on their dominant hand, measuring grip strength, touch sensitivity, pain threshold, and reaction tim…