HEALTHY VOLUNTEERS

This early-stage study tested a new meningococcal B vaccine in 576 healthy people, from infants to adults. Researchers checked for side effects and measured immune responses, comparing the new vaccine to two already-approved ones. The goal was to see if the vaccine is safe and tr…

This early-stage study tested a new oral drug, ASP5502, for primary Sjögren's syndrome, an autoimmune condition causing dry eyes and mouth. It involved 116 healthy adults and patients to check safety and how the body processes the drug. The study was terminated, but results may g…

This study tested an experimental drug called PF-07258669 in older adults (ages 60 to under 90) who were at risk of malnutrition or had unintended weight loss. The goal was to see if the drug is safe and whether it can help increase appetite and body weight. Participants took the…

This study tested three portable inhaler devices in 10 healthy adults to see how accurately they measure airflow and record breaths. No medication was used—only a harmless salt solution. The goal was to compare device performance and user comfort, not to treat any disease.

This study aimed to find substances in blood and urine that could signal kidney damage earlier than current tests. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure. Th…

This early-stage study tested the safety and tolerability of a new drug, AMG 378, in 48 healthy adults aged 18 to 55. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moves through the body. The study was terminated e…

This study tested whether a single session of non-invasive brain stimulation (alpha-tACS) could make people more flexible in their habits. Researchers compared real stimulation to a fake version in 7 healthy adults and heavy drinkers. The study was terminated early, so results ar…

This study worked on improving MRI scans of the lungs by having healthy volunteers inhale special tracer gases. The goal was to create clearer images of how the lungs work, not to treat any disease. The study involved 24 healthy people aged 6 to 75 and focused on developing bette…

This early-stage study tested two new liquid versions of the drug maribavir, designed for children, in 20 healthy adults. Researchers compared how the body absorbs these liquids versus the current tablet, and checked taste. The study was stopped early, so results are limited.

This study used anonymous online surveys to learn about vaping habits, mental health, and social influences among teens aged 13-18, as well as their parents' views. About 726 participants answered questions on vaping, drug use, mood, and gaming. The goal was to better understand …

This study tested a radiofrequency-based treatment on the skin of healthy volunteers and people with hidradenitis suppurativa (a painful skin condition). The main goal was to see if the treatment is safe and tolerable. The study was stopped early, but it aimed to understand how t…

This study looked at how healthy adults respond to breathing air with less oxygen for up to 7 days. Researchers measured oxygen levels in the blood, red blood cell production, and lung pressure to understand the body's adjustments. The goal was to define safety and basic response…

This early-stage study aimed to check the safety and tolerability of an experimental drug called iCP-NI in healthy adults aged 18 to 55. Participants received either the drug or a placebo through an IV. The study was terminated early, so results are limited.

This early-phase study tested a new radioactive drug called [11C]MC1 to see if it can help PET scans show inflammation in people with rheumatoid arthritis or inflammatory muscle disease. Healthy volunteers also took part to compare results. The study was terminated early, so find…

This study tested whether ultraviolet (UV-C) light can safely sanitize hands without the need for chemical sanitizers. Twenty-three healthy volunteers with light skin received UV-C or UV-B exposure, and small skin samples were taken to check for DNA damage. The trial was stopped …

This study looked at whether a mindfulness training program could change brain connections in teenagers who vape tobacco. Researchers used brain scans to see if these changes were linked to less vaping. The study was small and ended early, so results are limited.