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New brain scan agent could spot tumor recurrence vs. radiation damage

NCT ID NCT05676489

Not yet recruiting Diagnosis Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This first-in-human study will test a new radioactive imaging agent called MeFAMP to see if it can safely and accurately detect brain tumors using PET scans. The study includes 28 people: healthy volunteers and patients with recurrent high-grade glioma or brain metastases from other cancers. The goal is to measure safety, radiation exposure, and whether MeFAMP can tell the difference between active tumor and changes caused by prior radiation therapy.

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Conditions

The condition(s) this trial relates to.

glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN METASTASES FROM EXTRA-CRANIAL SOLID TUMORS HEALTHY VOLUNTEERS RECURRENT GLIOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UAB

    Birmingham, Alabama, 35294, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••