CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This study tested whether a daily under-the-tongue spray called MV130 could help adults with moderate to severe COPD. The goal was to see if this bacterial vaccine could reduce the number and severity of sudden worsening episodes (exacerbations) that people with COPD experience. …

This study compared two different triple-inhaler treatments for people with stable COPD to see which one better improves breathing and controls small airway disease. Twenty-two patients tried both treatments for four weeks each, with a break in between. Researchers measured lung …

This study compared the safety of a new inhaler device (HFO) to a standard one (HFA) for delivering the same triple-combination COPD medication. It involved 559 adults with moderate to very severe COPD over 12 weeks, with some continuing for a year. The main goal was to see if th…

This study looked back at the medical records of 718 people in Spain with chronic obstructive pulmonary disease (COPD) who started using a triple-combination inhaler called Trixeo Aerosphere. Researchers wanted to see what kinds of patients used this inhaler and how often they ex…

This study tested a new 'Auto-EPAP' feature on a specific breathing machine (Vivo 45 LS) to see if it could safely and effectively help keep people's airways open during sleep. It involved 23 adults who already use a breathing machine for conditions like sleep apnea, COPD, or obe…

This study observed how patients with moderate to severe COPD felt after starting a standard triple-inhaler medication (BGF MDI) in real Romanian clinics. It tracked changes in their self-reported breathing symptoms and treatment satisfaction over 6 months. The goal was to unders…

This study tested whether adding a specific breathing exercise, called the 4-7-8 technique, to standard medical care could help people with COPD. It involved 40 adults with mild to moderate COPD. Researchers compared the effects of the breathing exercise plus standard care agains…

This study tested whether inhaling L-menthol, which creates a cooling sensation in the airways, could help reduce the feeling of breathlessness in people with COPD. Twenty participants with COPD performed exercise tests after using either L-menthol or a placebo. The goal was to s…

This study compared two different breathing techniques to help people with COPD manage their symptoms. For four weeks, 58 participants tried either a device-based therapy (OPEP) or a self-guided breathing exercise (autogenic drainage). Researchers measured which method was better…

This study aimed to understand why people have different blood sugar, fat, and inflammation responses after eating the same meals. Over 1,600 participants from a larger heart and lung health study ate specific breakfasts and drank test meals at home over 10 days while their bodie…

This study aimed to understand how doing a mental task affects balance in people with Chronic Obstructive Pulmonary Disease (COPD). Researchers observed 36 people, some with COPD and some healthy, while they stood still and performed a memory task. The goal was to learn if the ex…

This study aimed to understand if Chronic Obstructive Pulmonary Disease (COPD) affects a person's ability to precisely control their leg muscle force during everyday movements. Researchers compared 36 people with COPD to healthy individuals by having them perform controlled leg c…

This early-stage study aimed to understand how a drug called cyclosporine, often used after organ transplants, might affect the body's processing of an experimental medication for COPD (CHF6001). Thirty healthy volunteers took the COPD drug alone and then again after taking cyclo…

This study aimed to better understand how Chronic Obstructive Pulmonary Disease (COPD) affects blood vessels in the lungs. Researchers used MRI scans to measure blood flow in the lungs of 30 people with COPD, both at rest and after light exercise. The goal was to gather informati…