CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This early-stage study investigates whether metformin, a medication typically used for diabetes, is safe and well-tolerated in older adults with COPD who do not have diabetes. Researchers will enroll 45 participants to see if metformin changes certain blood markers related to agi…

This study tests whether a 12-month training program led by physiotherapists can help people with COPD use their inhalers correctly. About 116 participants will be randomly assigned to receive either the special training sessions plus usual care, or just their usual care. The mai…

This small pilot study is testing whether a program where pharmacists help people with COPD (Chronic Obstructive Pulmonary Disease) manage their multiple medications is practical and acceptable. The goal is to see if this approach can make medicines safer to use and help reduce b…

This study is testing whether adding a traditional Chinese herbal medicine called Guben Kechuan Granules to standard care helps people with COPD recover better after a serious flare-up that required hospital care. Researchers will enroll 126 patients who are about to be discharge…

This study is testing whether a new injectable medication called JKN2401 can help control moderate-to-severe COPD. It will involve about 888 adults with COPD to see if the treatment safely reduces the number of serious symptom flare-ups they experience each year. Participants wil…

This study aims to understand how a daily triple-inhaler medication works in the lungs of people with moderate-to-severe COPD. Researchers will use a special type of MRI scan to see if the medication improves air flow in the lungs and how this relates to breathing tests and quali…

This is a very early study to test the safety of a new cell therapy called REGEND007 for people with COPD. The therapy uses special stem cells from the airways that may help repair damaged lung tissue. Researchers will give the cells through an IV to 12 participants and closely m…

This study aims to develop a faster, simpler way to screen for pulmonary embolism, a serious condition where a blood clot blocks an artery in the lungs. Researchers will test if a 1-minute heart rhythm recording from a smartphone device, analyzed by artificial intelligence, can a…

This study is testing whether a new, handheld ultrasonic device can measure lung function as accurately as the larger, standard machines used in hospitals. About 100 adults with chronic lung conditions like COPD or asthma will perform breathing tests using both devices. The goal …

This study is testing if a special, fast-paced video training method can help people with severe COPD who use a home breathing machine. The goal is to see if this training makes patients feel more confident managing their condition, reduces their symptoms like shortness of breath…

This study is testing if special 'active' sports shoes, designed to make walking easier, can help people with severe COPD. Seventy-five hospitalized patients will take two standard walking tests—one in their usual shoes and one in the special shoes—to see if they can walk farther…

This study aims to find out if giving extra oxygen during a walking test helps people with chronic lung conditions like COPD or interstitial lung disease. Researchers will have 114 hospitalized patients perform two 6-minute walking tests—one with their usual oxygen level and one …

This study is testing a wearable patch system designed to monitor lung function in adults with COPD from their own homes. For about 10 months, participants will wear the patch daily and also use a standard handheld breathing test device to see how well the patch's measurements co…

This study aims to find out if a simple breath test, which measures a gas called nitric oxide, can help predict which COPD patients are more likely to have serious flare-ups after starting a standard triple inhaler treatment. Researchers will follow 120 patients for one year to s…