CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This study looks at whether adding Guben Kechuan Granules to standard care helps people with COPD recover better after a sudden worsening of symptoms. About 126 adults aged 40-75 will take the granules or a placebo for 12 weeks. Researchers will measure lung function, breathing d…

This study is a safety check required by Korean health authorities. It will follow 600 adults with COPD who are starting Breztri to see how well the drug works and what side effects occur in everyday use. The goal is to confirm the drug's safety in a real-world setting, not to fi…

This study looks at how a once-daily triple inhaler (fluticasone furoate, umeclidinium, and vilanterol) helps adults with COPD who have ongoing moderate-to-severe breathing trouble or poor health. About 60 participants, aged 50-85, will take the inhaler daily for 12 weeks (with a…

This study tests an investigational injection called JKN2401 in people with moderate-to-severe COPD. The goal is to see if it can safely reduce the number of serious flare-ups (exacerbations) compared to a placebo. About 888 adults with a history of COPD exacerbations will partic…

This study aims to see if a one-minute recording of the heart's electrical activity (ECG), analyzed by a computer model, can help screen for pulmonary embolism (a serious blood clot in the lungs). Researchers will enroll 500 adults who need testing for this condition. They will c…

This study looks at whether different ways of breathing out (pursed-lip breathing with ratios 1:3, 1:4, or 1:5) can help people with COPD breathe easier. About 122 adults aged 40+ with stable COPD will try one of these breathing patterns for 10 minutes. Researchers will measure b…

This study looks at whether teaching people with COPD special energy-saving techniques can make daily tasks like washing or carrying easier and less tiring. About 70 adults with advanced COPD will learn these methods and be compared to a control group. The goal is to see if this …

This study tests a 12-month program led by physiotherapists to help people with COPD use their inhalers correctly. Many patients make errors that prevent medication from reaching the lungs, worsening symptoms. The program includes hands-on training and device checks to improve te…

This study tests whether a special breathing exercise device can make the diaphragm thicker and move better in people with stable COPD. Fifteen adults aged 40-59 with moderate COPD will do the training. Researchers will use ultrasound to measure changes in the diaphragm and stand…

This study looks at whether metformin, a diabetes drug, is safe and tolerable for people aged 65 and older with COPD who do not have diabetes. Researchers will check blood markers linked to aging and track side effects. The goal is to see if metformin can be used to help manage C…

This pilot study tests whether a pharmacist-led medication management program can help adults with COPD and other health conditions use their inhalers correctly and reduce shortness of breath. About 92 participants will receive inhaler teaching and medication counseling. The stud…

This study looks at whether a special training method called Pecha Kucha can help people with COPD who use a breathing machine at home. The training aims to improve patients' confidence in managing their symptoms, reduce symptom severity, and make daily activities easier. Sixty a…

This study tests whether wearing special 'active' sports shoes can help people with severe COPD walk farther during a six-minute walk test compared to their usual shoes. The shoes are designed with cushioning and rocker soles to store and return energy, which may make walking eas…

This study tests a wearable patch called WearME-Pro that aims to monitor lung function in adults with COPD from home. Over 10 months, 82 participants will use the patch and a standard handheld spirometer to see how well the patch measures breathing. The goal is to see if the patc…

This study looks at whether a breath test called FeNO can help predict serious flare-ups in people with COPD who are starting triple inhaler therapy. Researchers will follow 120 adults for one year to track flare-ups, lung function, and symptoms. The goal is to see if FeNO levels…

This study looks at how breathing in wildfire smoke can lead to long-term lung problems like asthma, COPD, and lung cancer. Researchers will safely expose 24 healthy adults to different levels of smoke in a controlled setting. The goal is to learn who is most at risk and what bio…

This study compares a small, portable ultrasonic spirometer with the standard hospital spirometer in 100 adults with chronic lung diseases like COPD or asthma. Each participant will take lung function tests using both devices to see if the handheld one gives accurate and reliable…