CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This study tests whether omega-3 fatty acids or vitamin D supplements can help people with COPD who are losing weight and muscle (a condition called pulmonary cachexia). Researchers will compare the effects of each supplement on body composition, strength, appetite, and fatigue i…

This study tests an investigational drug called tozorakimab in about 1,450 adults with symptomatic COPD who have had at least two moderate or one severe flare-up in the past year. Participants must already be on standard inhaled therapy. The main goal is to see if the drug can re…

This study tests an investigational drug called tozorakimab in adults with symptomatic COPD who have had at least two moderate or one severe flare-up in the past year and have high levels of eosinophils (a type of white blood cell). Participants receive either tozorakimab or a pl…

This study tests a new dry powder inhaler called HSK39004 in 180 adults aged 40 to 80 with COPD. The goal is to see if it improves lung function over 4 weeks compared to a placebo. Participants are randomly assigned to receive either the drug or an inactive inhaler, and neither t…

This study follows 152 adults with COPD who start taking a three-in-one inhaler (budesonide/glycopyrronium/formoterol, or BGF) as part of their routine care. Researchers want to see how the treatment affects symptoms, quality of life, and the number of flare-ups over six months. …

This study tests a drug called tozorakimab in people with COPD who have had flare-ups in the past. The goal is to see if it can reduce the number of severe breathing attacks over time. About 1,700 adults who completed earlier studies will take either the drug or a placebo for lon…

This study is testing whether an artificial intelligence (AI) system can detect chronic obstructive pulmonary disease (COPD) by analyzing cough sounds recorded on a smartphone. Researchers will collect cough audio and health data from 3,000 adults with and without COPD to train a…

This study tests whether using mild electrical pulses on the leg muscles can improve confidence in exercise, reduce shortness of breath during activity, and lessen fatigue in people with chronic lung disease (COPD). About 40 adults with mild to severe COPD will receive the stimul…

This study tests a new device called SonoHeal to see if it is easy and comfortable for people with cystic fibrosis, bronchiectasis, or COPD to clear mucus from their lungs. About 15 people will try the device and compare it to their usual treatment. The goal is to see if SonoHeal…

This study looks at over 1,500 people in Russia with moderate-to-severe COPD who have frequent lung attacks (exacerbations). Researchers will collect information on their health habits, other illnesses, and current treatments to better understand this group. The goal is to descri…

This study tests whether a wearable skin sensor can tell how much pain a person is feeling. Thirty-seven adults with cancer or COPD will wear the device for up to a week and rate their pain. The goal is to create an algorithm that automatically detects rising pain levels and aler…

This study looks at how well people with COPD can imagine doing movements, like reaching or bending, compared to people without the disease. Researchers will use questionnaires and a pegboard test to measure both the vividness and timing of these mental images. The goal is to bet…

This pilot study tests whether giving air cleaners and air quality monitors to 20 older adults with COPD can help them avoid flare-ups during smoky periods. Participants are Kaiser Permanente members who use oxygen and don't smoke. The main goal is to see if the approach is pract…

This study looks at how the health of blood vessels and a person's genes might be linked to early signs of COPD and emphysema. Researchers followed over 4,300 adults from a larger heart study, measuring lung function and using CT scans to check for lung damage. The goal is to bet…

This study looks at how often people with COPD have bladder problems (like leaking urine) and how much they know about pelvic floor health. Researchers will ask 30 adults with COPD to fill out questionnaires about their bladder symptoms and quality of life. The goal is to better …