CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This pilot study tests whether giving N95 masks and indoor air cleaners to 20 older adults with COPD can reduce lung flare-ups during poor air quality from wildfires. Participants are Kaiser Permanente members aged 65+ who use oxygen. The study focuses on whether this approach is…

This study tests an experimental drug called astegolimab against a placebo in 1290 people with COPD who have frequent flare-ups. Participants are current or former smokers. The main goal is to see if the drug reduces the number of moderate to severe COPD attacks over one year.

This study tests an experimental inhaler called HSK39004 in 180 adults with COPD, a long-term lung disease that makes breathing hard. Participants will use the inhaler or a placebo for 4 weeks to see if it safely improves lung function. The goal is to control the disease and ease…

This study tests a drug called tozorakimab in people with chronic obstructive pulmonary disease (COPD) who have a history of flare-ups and high levels of eosinophils (a type of white blood cell). The trial involves 98 participants who receive either tozorakimab or a placebo every…

This study tests an investigational drug called tozorakimab in about 1,454 adults with symptomatic COPD who have had at least two moderate or one severe flare-up in the past year. Participants continue their usual inhaled medications and receive either tozorakimab or a placebo as…

This study is testing whether an artificial intelligence program can detect chronic obstructive pulmonary disease (COPD) by analyzing cough sounds recorded on a smartphone. Researchers will collect cough recordings and medical data from 3,000 adults in China, both with and withou…

This pilot study tests whether an 8-week mindfulness program (MBSR) can reduce anxiety, depression, and stress in people with COPD who are already in pulmonary rehab. About 44 participants will be followed for 12 months. The goal is to see if this mind-body approach improves emot…

This study tests a new device called SonoHeal that uses sound waves to help people with cystic fibrosis, bronchiectasis, or COPD clear mucus from their lungs. Fifteen participants will try the device at home to see if it is easy to use and acceptable. The study also compares it t…

This study tests whether using a device that sends mild electrical pulses to the leg muscles can help people with COPD feel more confident about exercise, reduce shortness of breath during activity, and lessen fatigue. Forty patients with mild to severe COPD will receive the stim…

This study looks at over 1,700 people in Russia who have moderate to severe COPD and often have flare-ups. Researchers will collect information on their health, lifestyle, and treatments to better understand the disease. The goal is to learn more about these patients to help impr…

This study explores how problems with blood vessel function and genetics may contribute to early-stage COPD and emphysema. Researchers followed over 4,300 adults from a larger heart study, measuring lung function and CT scans. The goal is to understand risk factors, not to test a…

This study tests whether a wearable skin sensor can tell the difference between mild, moderate, and severe pain in 37 adults with cancer or COPD. Participants wear the device for up to a week and report their pain levels. The goal is to create an algorithm that alerts caregivers …

This study looks at whether people with COPD can imagine movements as clearly as those without the disease. Researchers will compare 188 participants using questionnaires and timing tests. The goal is to better understand how COPD might affect the brain's ability to picture and f…

This study aims to find out how common lower urinary tract symptoms (like leaking or trouble emptying the bladder) are in people with COPD, and how much they know about pelvic floor health. Researchers will ask 30 participants to fill out questionnaires about their breathing, bla…