New hope for COPD sufferers: drug targets high eosinophils to cut Flare-Ups

NCT ID NCT06897748

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called tozorakimab in people with chronic obstructive pulmonary disease (COPD) who have a history of flare-ups and high levels of eosinophils (a type of white blood cell). The trial involves 98 participants who receive either tozorakimab or a placebo every two weeks for 12 weeks. The goal is to see if the drug improves lung function and reduces the number of COPD exacerbations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tozorakimab

What this could lead to

If successful, tozorakimab could become a new treatment option to reduce COPD flare-ups and improve breathing in patients with high eosinophils.

What could go wrong

This is an early Phase 2 trial with only 98 participants, so results may not apply to all COPD patients. The drug may not improve lung function or reduce exacerbations significantly, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Aramil, 624002, Russia

  • Research Site

    Izhevsk, 426061, Russia

  • Research Site

    Moscow, 105554, Russia

  • Research Site

    Moscow, 117546, Russia

  • Research Site

    Moscow, 119048, Russia

  • Research Site

    Moscow, 125284, Russia

  • Research Site

    Omsk, 644099, Russia

  • Research Site

    Penza, 440067, Russia

  • Research Site

    Perm, 614000, Russia

  • Research Site

    Saint Petersburg, 193231, Russia

  • Research Site

    Saratov, 410054, Russia

  • Research Site

    Ulyanovsk, 432009, Russia