ATRIAL FIBRILLATION (AF)

This study compares a new blood thinner called abelacimab to the standard drug rivaroxaban in about 1,300 people with atrial fibrillation (an irregular heartbeat) who are at moderate-to-high risk of stroke. The main goal is to see if abelacimab causes fewer serious or nuisance bl…

This study tests whether specially trained pharmacists can help people with atrial fibrillation (an irregular heartbeat) take their blood-thinning medications more consistently. About 400 adults who are starting or already on these drugs will receive either personalized pharmacis…

This study tests a new device (TactiFlex SE catheter and Volt generator) that uses pulsed field ablation to treat paroxysmal atrial fibrillation, a type of irregular heartbeat. About 188 people with symptomatic AFib that hasn't responded to medication will receive the procedure. …

This study looks at 300 adults in Asia who had a heart ablation for atrial fibrillation. It compares giving the blood thinner heparin as a steady drip versus as occasional shots. The goal is to see which method keeps blood clotting time in the ideal range (250-350 seconds) to red…

This study looks at whether people with recent-onset atrial fibrillation (AFib) who get a heart ablation procedure right from the emergency room have fewer heart rhythm problems over the next year compared to those who get standard treatment. About 350 adults with AFib that start…

This study tests a device called Amulet 2 that plugs a small pouch in the heart (the left atrial appendage) where clots often form in people with atrial fibrillation. The goal is to lower stroke risk without needing lifelong blood thinners. About 458 participants with AF and high…

This study compares two ways to perform catheter ablation for atrial fibrillation (AFib), a common heart rhythm problem. One method uses X-ray guidance, while the other uses a non-fluoroscopic lab that avoids radiation. Researchers want to see if the non-fluoroscopic approach is …

This study is testing whether a newer MRI contrast agent called Gadopiclenol can produce clearer images of heart damage in people with atrial fibrillation (AF) compared to standard agents, while using a lower dose. About 50 adults with AF will receive a research MRI scan, and the…

This study looks at whether using a special blood pressure monitor at home can find atrial fibrillation (an irregular heartbeat) sooner in older adults with high blood pressure. About 1,900 people aged 60 and older will take daily readings and answer app surveys for up to 18 mont…

This study tests whether an artificial intelligence program can predict who has undiagnosed atrial fibrillation (AF) using a simple handheld ECG device used at home. About 200 adults aged 50-90 will use the device and complete surveys. The goal is to see if this approach can dete…

This study tests whether smartphones can accurately detect atrial fibrillation (AF), a common heart rhythm problem that raises stroke risk. About 209 adults with and without AF will use their phone's microphone, camera, and a small external sensor to record heart sounds, electric…

This study tests two methods to close the blood vessel after a common heart procedure for atrial fibrillation. One uses a special disc called StatSeal, the other uses a stitch. The goal is to see which helps patients get up and walk sooner, stop bleeding faster, and feel more com…

This study looks at people with atrial fibrillation (an irregular heartbeat) whose first heart ablation didn't work. It compares the usual repeat procedure with one that also treats an extra area of the heart, to see which helps patients feel better and have fewer heart rhythm pr…

This study looks at 1,000 adults aged 65 and older with atrial fibrillation who get their care at family health centers in Ordu, Türkiye. Researchers will check if patients are taking the correct dose of their blood thinner and how often they take it as prescribed. No new treatme…

This study looks at whether a new algorithm can predict if atrial fibrillation (AF) will come back after a common heart procedure called pulmonary vein isolation. Researchers will review records from 300 people who had this procedure to see if the algorithm's predictions match wh…

This study watches 40 adults who need a leadless pacemaker (Micra AV) to see if where the device sits inside the heart changes the heart's electrical signals or pumping ability. Researchers will use CT scans and ECGs to measure heart function and valve leakage. The goal is to fin…

This study compares six different 7-day ECG patches in adults aged 65 and older who need heart monitoring as part of their regular care. The goal is to see which patches provide the most usable heart rhythm recordings over a week. No new treatments or medications are being tested…

This study looks at a new method to analyze electrical signals in the heart to help doctors know exactly where to burn (ablate) abnormal tissue causing atrial fibrillation (AFib). Researchers will study data from 336 people who had AFib ablation, comparing those who stayed free o…

This study looks at how doctors use the FARAPULSE system to treat atrial fibrillation (an irregular heartbeat) in real-world settings. Researchers will collect data from 524 patients to see which steps before, during, and after the procedure work best. The goal is to improve safe…

This study looks at whether family doctors can be trained to perform focused heart ultrasounds (FoCUS) accurately. About 500 patients with suspected heart issues will have both a doctor-performed ultrasound and a standard cardiologist exam. The goal is to see how well the doctors…

This study is testing whether monthly heart rhythm checks (ECGs) at local family health centers can find undiagnosed atrial fibrillation in adults aged 65 and older. About 1000 participants in Ordu, Turkey, will get a quick, painless ECG every month for a year. If a new irregular…

This study tests whether a smartwatch (Apple Watch or PulseOn) can detect hidden atrial fibrillation (AF) in 84 stroke survivors who already have an implanted heart monitor. Participants wear the watch for 12 weeks, and the watch alerts them if it senses an irregular pulse. The g…

This study looks at a possible side effect of a heart treatment called Pulsed Field Ablation (PFA) for atrial fibrillation. The treatment can sometimes injure the phrenic nerve, which controls the diaphragm muscle used for breathing. Researchers will use a special X-ray before an…