ATRIAL FIBRILLATION (AF)

This study tested a single, combined surgical and catheter procedure to treat complex atrial fibrillation (AF) in 12 people. The approach uses keyhole surgery on the outside of the heart and, if needed, a catheter inside the heart to create a complete set of lesions. The goal was…

This study looked at whether rebamipide, alone or with pantoprazole, can prevent stomach problems like bleeding or ulcers in people with atrial fibrillation who take blood thinners. About 210 adults aged 18-80 with moderate to high stroke risk participated. They received one of t…

This study tested a systematic workflow called the '12 Commandments' for a type of heart ablation (pulsed-field ablation) in 118 people with atrial fibrillation. The goal was to see if this approach could better keep the heart's pulmonary veins isolated after treatment, reducing …

This study tested a therapist-assisted online program (HOPE-AF) designed to prevent depression in 28 adults with atrial fibrillation. Participants used modules and communicated with a therapist to address worry and anxiety. The goal was to see if the program was acceptable and ea…

This study tested three different drug combinations to keep patients comfortably sedated during a heart procedure called pulsed field ablation for atrial fibrillation. 240 adults with AF were randomly assigned to one of three sedation groups. The goal was to see which approach be…

This study tested a new step-by-step ablation method guided by voltage readings against the standard approach for treating atrial fibrillation (AF). 130 adults with AF having their first ablation were randomly assigned to one of the two methods. The goal was to see if the new tec…

This study looked at 40 adults with atrial fibrillation (a type of irregular heartbeat) to compare two ways of performing a procedure that isolates the veins carrying blood from the lungs to the heart. One method uses a special mapping system, while the other relies on X-ray guid…

This study tested whether an augmented reality (AR) tool, accessed via a QR code on a smartphone, could help heart patients better understand their discharge instructions. Over 300 adults hospitalized for heart attack, heart failure, atrial fibrillation, or pacemaker implantation…

This study checked if a generic version of dronedarone (a drug for atrial fibrillation) works the same as the brand-name drug MULTAQ®. Fifty-one healthy adults took one dose of each under fasting conditions. The goal was to see if the generic is absorbed similarly, not to treat a…

This study looked at two different methods for a key step in treating atrial fibrillation (AF) called transseptal puncture, but without using any X-ray. The goal was to see which technique is safer and faster for doctors and patients. 28 adults with AF took part, and the research…

This study involved 172 people with atrial fibrillation who were having a heart procedure. Researchers found a common imaging artifact called the 'Floating Lotus' sign that can look like a dangerous blood clot but is actually harmless. By describing this sign and how to tell it a…

This pilot study involved 9 people with atrial fibrillation undergoing a standard pulsed field ablation procedure. Researchers tested a new algorithm that measures heart signals in real time to see if it works as well as manual measurements. The goal was to gather data and improv…

This study checked if a generic version of the heart drug dronedarone (400 mg tablets) works the same as the brand-name drug MULTAQ®. It involved 48 healthy Chinese adults and measured drug levels in the blood after eating. The goal was to confirm the generic is a safe and effect…

This study tested whether using a 3D-printed model of a patient's heart helps doctors perform a procedure to prevent strokes in people with atrial fibrillation. About 184 adults with non-valvular atrial fibrillation who were at high risk for stroke and couldn't take blood thinner…

This study tested a new way of breathing during a common heart procedure for atrial fibrillation. The goal was to see if using very small, fast breaths with controlled pressure could keep the treatment catheter more stable. 52 adults took part, and researchers compared the new br…

This study checked if an artificial intelligence program called ZywieAI can correctly analyze heart rhythm data collected from a small wearable sensor worn on the chest for 24 hours. 153 adults wore the sensor, and the AI's findings were compared to reviews by heart specialists. …

This study tested whether using a 3D heart map during pulsed field ablation (a procedure to treat atrial fibrillation) helps doctors deliver more precise burns to the right spots. Thirty-two adults with AF were randomly assigned to get the procedure with or without the 3D map. Th…