Which sedation works best for atrial fibrillation ablation?

NCT ID NCT07149545

Completed Symptom relief Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested three different drug combinations to keep patients comfortable and still during a heart procedure called pulsed field ablation for atrial fibrillation. 240 adults were randomly assigned to one of three sedation groups. The goal was to see which method achieved the right level of sedation without causing breathing or blood pressure problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fentanyl, Midazolam, Flurbiprofen axetil, Dexmedetomidine
What this could lead to: If successful, this could identify a safer and more effective sedation method for patients undergoing pulsed field ablation for atrial fibrillation.
What could go wrong: This is a single-center, completed trial with a focus on sedation success, not long-term outcomes. Results may not apply to all hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation PFAPA syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) DEEP SEDATION PFA

Contacts and locations

Locations

Beijing Anzhen Hospital

Beijing, Beijing Municipality, 100029, China

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