Which sedation works best for atrial fibrillation ablation?
NCT ID NCT07149545
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested three different drug combinations to keep patients comfortable and still during a heart procedure called pulsed field ablation for atrial fibrillation. 240 adults were randomly assigned to one of three sedation groups. The goal was to see which method achieved the right level of sedation without causing breathing or blood pressure problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fentanyl, Midazolam, Flurbiprofen axetil, Dexmedetomidine
What this could lead to
If successful, this could identify a safer and more effective sedation method for patients undergoing pulsed field ablation for atrial fibrillation.
What could go wrong
This is a single-center, completed trial with a focus on sedation success, not long-term outcomes. Results may not apply to all hospitals or patient groups.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Anzhen Hospital
Beijing, Beijing Municipality, 100029, China