ANATOMIC STAGE III BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE III BREAST CANCER AJCC V8 explained in plain language.
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Custom-Made vaccine takes on tough breast cancer
⭐️ VACCINE ⭐️ Recruiting nowThis early-stage trial tests a personalized vaccine made from a patient's own tumor, combined with drugs that boost the immune system (pembrolizumab or ipilimumab), for triple negative breast cancer. The goal is to see if the vaccine is safe and can help the immune system attack …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 08, 2026 13:08 UTC
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BREAST CANCER BREAKTHROUGH: thousands could avoid unnecessary treatment
Disease control Recruiting nowThis study is for people with early-stage triple-negative breast cancer whose tumors completely disappeared after initial chemotherapy plus immunotherapy (pembrolizumab). It compares the usual approach of continuing pembrolizumab for 27 more weeks versus simply watching and waiti…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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New study tests cheaper drug to block estrogen in breast cancer
Disease control Recruiting nowThis study compares two drugs, leuprolide and goserelin, to see how well they lower estrogen levels in premenopausal women with breast cancer. Both drugs work by temporarily stopping the ovaries from making estrogen, which can fuel cancer growth. The trial will enroll 75 women an…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Immunotherapy boost may stop High-Risk breast cancer from returning
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (durvalumab) to standard chemotherapy can better prevent breast cancer from coming back in people with a high-risk type of hormone receptor-positive, HER2-negative breast cancer. About 3,680 adults with stage II or III breast …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:48 UTC
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Custom-Made vaccine plus immunotherapy shows promise for advanced cancers
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, given alone or with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps control t…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 19:09 UTC
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New vaccine combo aims to supercharge immune attack on breast cancer
Disease control Recruiting nowThis study tests whether adding a cancer vaccine (WOKVAC) to standard chemotherapy and HER2-targeted therapy before surgery can help the immune system better attack breast cancer. About 25 adults with early-stage HER2-positive breast cancer will receive the vaccine alongside thei…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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New drug cocktail aims to shrink Hard-to-Treat breast cancer
Disease control Recruiting nowThis early-phase study tests whether adding an experimental drug (ASTX727) to standard chemotherapy and immunotherapy can safely shrink or stabilize tumors in people with metastatic triple-negative breast cancer that cannot be removed by surgery. About 32 adults will take part to…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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5-Day breast radiation: a game changer for cancer patients?
Disease control Recruiting nowThis study tests a new, ultra-short radiation schedule for women with stage I-III breast cancer who have had a lumpectomy. Instead of weeks of daily radiation, the whole breast and surgical cavity are treated together over just 5 days. The goal is to see if this approach controls…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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New study aims to help latina breast cancer survivors lose weight and live healthier
Disease control Recruiting nowThis study tests two remote weight loss programs designed for Latina breast cancer survivors who have finished initial cancer treatment. The goal is to help participants lose weight and improve their long-term health. Researchers will enroll 640 women to see which approach works …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:01 UTC
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New hope for Hard-to-Treat cancers: targeted pill shows promise in DNA-Repair defect tumors
Disease control Recruiting nowThis study is testing a daily pill called talazoparib in people with advanced solid tumors (like breast, prostate, ovarian, or pancreatic cancer) that have specific DNA repair gene mutations. The drug works by blocking a protein that helps cancer cells fix their DNA, causing them…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New combo therapy offers hope for Hard-to-Treat breast cancer
Disease control Recruiting nowThis study tests whether combining tamoxifen (a hormone blocker) with a targeted form of chemotherapy (liposomal doxorubicin) can shrink tumors in people with advanced triple-negative breast cancer that has spread or cannot be removed by surgery. The trial enrolls 30 adults who h…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New triple-drug attack shows promise against hard-to-treat breast cancer
Disease control Recruiting nowThis early-phase trial tests whether adding an experimental drug (ZEN003694) to standard immunotherapy (pembrolizumab) and chemotherapy (nab-paclitaxel) is safe and tolerable for people with advanced triple-negative breast cancer that has spread. About 57 participants will receiv…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New combo aims to outsmart Hard-to-Treat HER2 cancers
Disease control Recruiting nowThis early-phase trial tests whether adding pidnarulex to the targeted therapy trastuzumab deruxtecan is safe and effective for people with advanced HER2-expressing breast cancer or other solid tumors that have spread or can't be removed. About 36 adults whose cancer has stopped …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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Electric field device joins forces with cancer drugs in early trial
Disease control Recruiting nowThis early-phase study tests a wearable device that creates electric fields (tumor treating fields) combined with either cabozantinib or a chemo-immunotherapy pair (nab-paclitaxel and atezolizumab) in people with advanced solid tumors in the abdomen or chest. The goal is to find …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Could less chemo be better for older breast cancer patients?
Disease control Recruiting nowThis study looks at whether giving a lower dose of two chemotherapy drugs (docetaxel and cyclophosphamide) can work well and cause fewer side effects in women aged 65 and older with early-stage HER2-negative breast cancer. The goal is to help these women complete their treatment …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Heart drug may reboot immune attack on stubborn breast cancer
Disease control Recruiting nowThis study tests whether adding a common heart medication (propranolol) to an immunotherapy drug (pembrolizumab) can help the immune system recognize and attack triple-negative breast cancer that has stopped responding to standard treatment. About 37 adults with advanced, incurab…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 11, 2026 11:57 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase study tests the safety and best dose of two drugs, ZEN003694 and abemaciclib, given together. It is for people with advanced breast cancer, NUT carcinoma, or other solid tumors that have spread or cannot be removed by surgery. The goal is to see if the combinatio…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 05, 2026 12:06 UTC
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New combo therapy aims to outsmart drug resistance in hereditary breast cancer
Disease control Recruiting nowThis study tests whether adding cediranib or AZD6738 to olaparib can overcome resistance in people with advanced or metastatic breast cancer who have a BRCA gene mutation. About 60 participants will receive one of the combination treatments. The goal is to see if these combos can…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 03, 2026 12:02 UTC
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Breast cancer survivors may get a new tool to fight diabetes risk
Disease control Recruiting nowThis study looks at whether the diabetes drug metformin can help women with stage I-III breast cancer who have finished chemotherapy avoid or reverse insulin resistance, a condition that can lead to diabetes and heart disease. About 200 women will either receive metformin plus st…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 27, 2026 12:02 UTC
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New ultrasound technique may predict chemo success early in breast cancer
Diagnosis Recruiting nowThis study tests whether a special type of ultrasound, using a contrast dye called Definity, can measure pressure inside breast tumors to predict how well chemotherapy is working. About 200 women with locally advanced breast cancer will get three of these ultrasounds before and d…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: Kibo Nam • Aim: Diagnosis
Last updated May 29, 2026 14:18 UTC
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New procedure aims to stop arm swelling before it starts
Prevention Recruiting nowThis study tests whether doing a lymphovenous bypass during lymph node surgery can prevent lymphedema (arm swelling) in people with breast cancer or melanoma. The bypass creates a new path for fluid to drain away from the arm. Researchers will compare swelling rates in 252 partic…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Jun 16, 2026 22:21 UTC
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Tailored exercise may protect heart and fitness in breast cancer patients on chemo
Symptom relief Recruiting nowThis study tests whether a personalized virtual exercise program, combined with health education, helps breast cancer patients maintain their ability to exercise, heart health, and quality of life during chemotherapy. About 120 adults with stage I-III breast cancer scheduled for …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 16, 2026 22:36 UTC
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Can a baldness drug save hair during breast cancer treatment?
Symptom relief Recruiting nowThis study looks at whether minoxidil (a hair growth drug) can help with hair loss caused by hormone therapy in breast cancer patients. About 50 women with stage I-IV breast cancer who are on hormone therapy and have noticed hair thinning will either take minoxidil pills or apply…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 16, 2026 12:55 UTC
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Brain food: MIND diet may fight chemo fog in breast cancer patients
Symptom relief Recruiting nowThis study tests whether a 12-week MIND eating plan can reduce memory problems, fatigue, and other symptoms in women with stage II-III triple-negative breast cancer during chemotherapy. About 60 women will be randomly assigned to either the MIND diet or general health coaching, w…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:05 UTC
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New radiation approach could cut treatment time and side effects for breast cancer patients
Symptom relief Recruiting nowThis study compares giving a shorter, stronger course of radiation (hypofractionated radiotherapy) either before or after breast cancer surgery. The goal is to see which timing causes fewer serious side effects while still being effective. About 120 adults with non-metastatic bre…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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Acupuncture may help black women avoid debilitating joint pain during breast cancer treatment
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It focuses on Non-Hispanic Black women with early-stage breast cancer, who are more likely to stop treatment du…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated Jun 15, 2026 19:02 UTC
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Laser therapy offers hope for breast cancer survivors suffering from vaginal dryness
Symptom relief Recruiting nowThis study tests a laser treatment for vaginal dryness in breast cancer survivors. Many survivors experience this side effect from cancer treatments like chemotherapy or hormone therapy. The trial will compare the laser to no treatment in 250 women to see if it improves symptoms.
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Potato starch may ease joint pain in breast cancer patients
Symptom relief Recruiting nowThis study tests whether a dietary supplement called resistant potato starch can help prevent joint pain and stiffness caused by aromatase inhibitors, a common breast cancer treatment. About 20 people with stage 0-III breast cancer or at high risk for it will take the supplement …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Stress relief trial aims to ease triple negative breast cancer journey
Symptom relief Recruiting nowThis study tests whether a 10-week stress reduction program is practical and helpful for women with early-stage triple negative breast cancer. The program teaches relaxation, coping skills, and communication, and also connects participants with social services for needs like tran…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 03, 2026 12:04 UTC
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Mayo clinic study aims to boost Self-Esteem in breast cancer survivors by improving skin health
Symptom relief Recruiting nowThis study looks at how aromatase inhibitor therapy affects skin quality and self-esteem in breast cancer survivors. Researchers will use special imaging to track skin changes in 35 women with early-stage, hormone-positive breast cancer. The goal is to understand and potentially …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 02, 2026 11:58 UTC
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Researchers track immune cells in HER2+ breast cancer patients
Knowledge-focused Recruiting nowThis study collects blood and tumor tissue from 230 adults with HER2-positive breast cancer (stages I–IV) who are starting anti-HER2 therapy. Researchers want to learn how the immune system reacts to treatments like trastuzumab and pertuzumab. The goal is to better understand the…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Can your social life help you beat Cancer's aftermath? new study investigates
Knowledge-focused Recruiting nowThis study looks at how personal relationships and physical activity influence the quality of life of young adults (ages 18-39) who have been diagnosed with cancer. Researchers will track 250 participants over time to see how social connections and exercise habits change and affe…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:52 UTC
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Breast cancer survivors needed for biobank study
Knowledge-focused Recruiting nowThis study collects blood samples and health information from 1,300 women who have had stage I-III breast cancer and finished active treatment. The goal is to create a biorepository that scientists can use in the future to explore links between genes, molecules, and long-term can…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:50 UTC
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DNA-Guided cancer therapy: a new hope for advanced tumors?
Knowledge-focused Recruiting nowThis study screens up to 2,900 people with advanced or hard-to-treat solid tumors to find genetic changes in their cancer cells. Based on those results, patients may be matched to a treatment trial that uses a combination of drugs targeting their specific mutations. The goal is t…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:09 UTC
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Can a PET scan predict which breast cancer patients will respond to treatment?
Knowledge-focused Recruiting nowThis study tests whether a special type of PET scan (FFNP-PET/CT) can predict how well a drug combination (abemaciclib plus hormone therapy) works in people with advanced hormone receptor-positive, HER2-negative breast cancer. About 60 participants with metastatic or locally adva…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:09 UTC
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Breast cancer and sleepless nights: new study investigates the link
Knowledge-focused Recruiting nowThis study looks at how sleep changes in women with early-stage breast cancer during treatment. Researchers will track sleep patterns and check for links to stress, social support, and living environment. About 100 participants will wear a sleep monitor and answer surveys before,…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:12 UTC
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Blood test may spot breast cancer resistance before It's too late
Knowledge-focused Recruiting nowThis study is looking at whether a blood test called DiviTum TKa can predict when hormone-receptor-positive, HER2-negative metastatic breast cancer stops responding to treatment. About 100 participants will give blood samples before and during their standard therapy. The goal is …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:25 UTC
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New ultrasound marker aims to improve breast cancer surgery guidance
Knowledge-focused Recruiting nowThis early-stage study tests a new type of marker that shows up better on ultrasound for people with breast cancer that has spread to lymph nodes. The marker is placed in the lymph node to help doctors find and remove the right node during surgery. The goal is to see if this mark…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:24 UTC
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New tool aims to help women with breast cancer make tough surgery choices
Knowledge-focused Recruiting nowThis study looks at whether a decision-making tool helps women newly diagnosed with early-stage breast cancer decide if they want preventive mastectomy on their healthy breast. About 15 participants will use the tool and rate how clear and balanced it is. The goal is to see if th…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 01, 2026 18:08 UTC