Can a PET scan predict which breast cancer patients will respond to treatment?

NCT ID NCT06179303

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special type of PET scan (FFNP-PET/CT) can predict how well a drug combination (abemaciclib plus hormone therapy) works in people with advanced hormone receptor-positive, HER2-negative breast cancer. About 60 participants with metastatic or locally advanced breast cancer will receive the treatment and have imaging before and during therapy. The goal is to see if changes in the scan can tell early on who is responding and who is not, helping doctors personalize treatment in the future.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

  • Siteman Cancer Center at Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

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