ANATOMIC STAGE III BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE III BREAST CANCER AJCC V8 explained in plain language.
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New drug combo shows promise in slowing advanced breast cancer
Disease control OngoingThis phase 3 trial tested whether adding the drug entinostat to standard hormone therapy (exemestane) helps people with advanced hormone receptor-positive breast cancer live longer without their cancer getting worse. The study included 608 adults whose breast cancer had spread or…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 01:37 UTC
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New triple therapy shows promise in Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests the safety and best dose of a three-drug combination (entinostat, nivolumab, and ipilimumab) in people with advanced solid tumors or HER2-negative breast cancer that has spread or cannot be removed. The goal is to see if this approach can help control…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 01:36 UTC
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New drug combo targets Hard-to-Treat cancers with gene mutations
Disease control OngoingThis early-phase study tests a new drug (AZD8186) combined with chemotherapy (docetaxel) in people with advanced solid tumors that have certain gene changes (PTEN or PIK3CB mutations). The main goals are to find the safest dose and understand side effects. About 23 adults whose c…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 01:34 UTC
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Texts and talks boost breast cancer Pill-Taking
Symptom relief OngoingThis study tests whether text message reminders and telephone counseling can help women with hormone-positive breast cancer take their daily endocrine therapy pills more consistently. About 1,167 women will either get usual care or extra support through texts and motivational cal…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Apr 29, 2026 01:35 UTC
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Chatbot could be new ally for breast cancer survivors battling insomnia
Symptom relief OngoingThis study looks at whether a chatbot called Cecebot can help breast cancer survivors with insomnia sleep better. About 60 women with stage I-III breast cancer who have trouble sleeping will use the chatbot, which sends text messages with tips from cognitive behavioral therapy an…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Apr 29, 2026 01:35 UTC
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New web tool aims to ease life for young breast cancer survivors
Symptom relief OngoingThis study tests a web-based tool called YES that helps young breast cancer survivors track and manage their symptoms. About 400 women aged 15-39 who had early-stage breast cancer in the last 3 years are taking part. The goal is to see if using the YES portal improves their quali…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Apr 29, 2026 01:35 UTC
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Walking through chemo: new study tests exercise in older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is practical for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will be asked to walk and do arm exercises several times a week during their treatment. The goal is to see if…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Apr 29, 2026 01:34 UTC
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Can a digital kitchen program boost diet in breast cancer survivors?
Symptom relief OngoingThis study tests a remotely-delivered nutrition and cooking program called MIND for people who had stage I-III breast cancer. The goal is to see if the program is practical and helps improve diet quality, like eating more fruits and vegetables. About 49 participants will use an o…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Apr 29, 2026 01:34 UTC
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Gene test may predict chemo nerve pain in black breast cancer patients
Knowledge-focused OngoingThis study tests whether a genetic marker can identify African American women with breast cancer who are at higher risk for nerve damage from chemotherapy drugs like Taxol or Taxotere. About 249 women with stage I-III breast cancer will be followed to see how their genes affect n…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Apr 29, 2026 01:37 UTC
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Gene test may match breast cancer patients to right therapy
Knowledge-focused OngoingThis study looks at whether genetic testing of tumor samples can help predict how well chemotherapy or hormone therapy will work for people with HER2-negative breast cancer (stages I to III). Researchers will analyze tumor genes to see if they can sort patients into groups that a…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 01:35 UTC
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New 'Twinkling' marker could make breast cancer surgery more precise
Knowledge-focused TerminatedThis early-stage study tests a new type of marker that shows up brightly on ultrasound, making it easier for surgeons to find and remove cancerous lymph nodes during breast cancer surgery. The study involves 15 adults with breast cancer that has spread to nearby lymph nodes. The …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 29, 2026 01:35 UTC