ANATOMIC STAGE III BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE III BREAST CANCER AJCC V8 explained in plain language.
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New vaccine aims to train immune system to fight triple negative breast cancer
⭐️ VACCINE ⭐️ OngoingThis study tests a DNA-based vaccine called STEMVAC in 33 people with early-stage triple negative breast cancer. The vaccine targets proteins found on breast cancer stem cells and aims to train the immune system to recognize and destroy these cells. The main goal is to see if the…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 09, 2026 12:08 UTC
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New drug cocktail aims to keep breast cancer at bay
Disease control OngoingThis study tests whether adding tucatinib to the standard drug T-DM1 can better prevent HER2-positive breast cancer from returning after initial treatment. About 1,056 people with early-stage HER2-positive breast cancer who still have cancer cells after initial therapy will take …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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New combo therapy shows promise for HIV patients with advanced cancer
Disease control OngoingThis early-phase trial tested the safety of combining two drugs, nivolumab and cabozantinib, in 8 people with HIV who also have advanced solid tumors. The goal was to see if the combination is safe and can shrink or stabilize the cancer. The study focused on finding the right dos…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase study tests a combination of two drugs, niraparib and dostarlimab, in 18 adults with BRCA-mutated breast, pancreas, or ovary cancer that has spread or cannot be surgically removed. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Experimental Triple-Drug combo targets Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests the safety and best dose of combining entinostat (a drug that may stop cancer cell growth) with two immunotherapy drugs, nivolumab and ipilimumab, in people with advanced solid tumors that have spread or cannot be removed by surgery. The goal is to se…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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New drug combo targets Hard-to-Treat HER2 cancers
Disease control OngoingThis early-stage study tests a combination of two drugs—trastuzumab deruxtecan (DS-8201a) and ceralasertib—in people with advanced solid tumors that have a HER2 mutation. The first part finds the safest dose and checks side effects. The second part compares the combo to DS-8201a …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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New combo therapy targets hard-to-treat breast cancer in phase 2 trial
Disease control OngoingThis study tests whether a drug called olaparib (a PARP inhibitor) works better alone or combined with atezolizumab (an immunotherapy) for people with advanced breast cancer that has a BRCA mutation and is not HER2-positive. About 81 participants with locally advanced or metastat…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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New drug combo targets Hard-to-Treat cancers
Disease control OngoingThis early-stage trial tests a new drug (BAY 1895344) combined with standard chemotherapy for people with advanced solid tumors, especially bladder cancer. The goal is to find the safest dose and see how well the combination works. About 74 adults with cancers like lung, ovarian,…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New drug combo shows promise in slowing advanced breast cancer
Disease control OngoingThis study tested whether adding the drug entinostat to standard hormone therapy (exemestane) helps people with advanced hormone receptor-positive breast cancer live longer without their cancer growing. About 600 adults with breast cancer that had spread or come back took part. T…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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New targeted therapy combo shows promise for HER2+ breast cancer
Disease control OngoingThis study tests a combination of targeted drugs (ribociclib, tucatinib, trastuzumab, with or without fulvestrant) for HER2-positive breast cancer. In the first part, it looks at safety in patients whose cancer has spread. In the second part, it compares these drugs to standard c…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Proton vs X-Ray: which radiation causes fewer side effects in breast cancer?
Disease control OngoingThis study compares two types of radiation therapy—standard x-ray and proton beam—for people with breast cancer who have had surgery. The goal is to see which method causes fewer serious side effects or unplanned surgeries over two years. About 146 adults with stage I to III brea…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New drug combo shows promise in Tough-to-Treat breast cancer
Disease control OngoingThis study tests two drugs, eribulin and copanlisib, together in people with metastatic triple-negative breast cancer that has spread or cannot be removed. The goal is to find the safest dose and see if the combination helps stop or slow tumor growth better than eribulin alone. A…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New drug combo shows promise for resistant breast cancer
Disease control OngoingThis study tests a new drug (TVB-2640) combined with standard treatments for people with HER2+ breast cancer that has spread and stopped responding to the usual therapy. The goal is to see if the combination can shrink or control the cancer. The trial involves 17 adults with adva…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Can estrogen fight a tough breast cancer? new trial explores
Disease control OngoingThis study tests if a form of estrogen (estradiol) can help people with a specific type of triple negative breast cancer that has spread. The cancer must have a protein called ER beta. The goal is to see if the estrogen can slow or shrink the cancer. About 8 adults with advanced …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Texts and calls boost breast cancer Pill-Taking in major trial
Disease control OngoingThis study tests whether adding text message reminders and/or telephone counseling helps breast cancer patients take their daily hormone therapy pills more consistently. About 1,167 women with early-stage, hormone-sensitive breast cancer will be followed for up to two years. The …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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New study aims to keep young breast cancer patients on lifesaving pills
Symptom relief OngoingThis study tests whether regularly checking in on symptoms, along with providing educational materials, helps young women with early-stage breast cancer continue taking their hormone therapy as prescribed. Hormone therapy can cause unpleasant side effects, leading some to stop ea…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated Jun 15, 2026 19:06 UTC
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New web tool aims to ease symptoms for young breast cancer survivors
Symptom relief OngoingThis study tests a web-based portal called YES that helps young breast cancer survivors track symptoms and find self-management resources. About 400 women aged 15-39 with early-stage breast cancer are taking part. The goal is to see if using the portal improves quality of life co…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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New program aims to boost quality of life for seniors after breast cancer
Symptom relief OngoingThis study tests a special check-up and support program for adults 65 and older who have finished treatment for early-stage breast cancer. The goal is to improve their overall health and quality of life by addressing physical, mental, and emotional needs. Participants will comple…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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Walking through chemo: new study tests exercise for older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is practical for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will be asked to walk and do arm exercises several times a week. The goal is to see if exercise can reduce th…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Can a digital kitchen program help breast cancer survivors eat healthier?
Symptom relief OngoingThis study tests a remote program that combines mindfulness with nutrition and cooking lessons to help breast cancer survivors eat better. About 49 people who had stage I-III breast cancer in the past 5 years will take part. The program is delivered online through the Cook for Yo…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Can yoga and nutrition help breast cancer survivors feel better? a new study aims to find out.
Symptom relief OngoingThis study looks at whether two different health programs are practical and liked by breast cancer survivors. About 106 people who finished treatment for early-stage breast cancer will try either an Ayurveda program (with diet, yoga, and touch therapy) or a self-guided online edu…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Writing away the pain: new study tests expressive writing for chinese breast cancer survivors
Symptom relief OngoingThis study looks at whether a culturally tailored writing program can improve the well-being of Chinese immigrant women who had breast cancer (stages 0 to III). About 256 women who finished their main cancer treatment in the last 5 years will write about their experiences. The go…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 02, 2026 11:57 UTC
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Cancer survivors share fertility hopes in new survey
Knowledge-focused OngoingThis study surveys women aged 18-45 who have had gynecological or breast cancer to learn how they think about having children after treatment. Researchers will use the survey results to better understand fertility concerns and help future patients make informed decisions about ca…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:37 UTC
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New study tracks shoulder pain after breast cancer radiation
Knowledge-focused OngoingThis study looks at shoulder and arm problems in 61 people with lymph-node positive breast cancer who receive radiation therapy. Researchers want to see how often these problems happen and how severe they are one year after treatment. The goal is to help doctors choose radiation …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:37 UTC
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Gene test may guide breast cancer therapy choices
Knowledge-focused OngoingThis study looks at whether a genetic test on tumor samples can predict how well HER2-negative breast cancer will respond to standard treatments like chemotherapy or hormone therapy. About 1,100 people with stage I-III breast cancer are taking part. The goal is to see if this tes…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Massive biobank aims to unlock Cancer's secrets
Knowledge-focused OngoingThis study collects tissue and blood samples, along with medical information, from 1,600 people with various advanced cancers. Researchers will track these samples over time to learn how cancer changes and why some treatments stop working. The goal is to build a resource for futu…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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New ultrasound marker could make breast cancer surgery more precise
Knowledge-focused TerminatedThis early-stage study tests a new type of marker that shows up brightly on ultrasound, helping surgeons locate cancer that has spread to lymph nodes in people with breast cancer. The marker is placed before chemotherapy and removed during surgery. The goal is to see if it stays …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:07 UTC
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Genetic test may predict chemo nerve pain in black women
Knowledge-focused OngoingThis study looks at whether a genetic test can identify African American women with breast cancer who are more likely to develop nerve damage from chemotherapy drugs like docetaxel or paclitaxel. About 249 women with stage I-III breast cancer will be enrolled. The goal is to see …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused TerminatedThis study looks at whether a blood test can find tiny amounts of cancer DNA left in the body after treatment for early-stage breast cancer. About 350 patients with stage I to III breast cancer will give blood samples to see if the test can help doctors decide who needs more ther…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC
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PET scans may guide breast cancer treatment decisions
Knowledge-focused OngoingThis study tests whether a special PET/CT scan can predict how well HER2-positive breast cancer responds to chemotherapy before surgery. About 235 adults with stage II-III breast cancer will get a scan early in treatment to see if it helps doctors decide if more or less chemo is …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:18 UTC
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Online support for cancer fear: study withdrawn before it began
Knowledge-focused TerminatedThis study was designed to see if a virtual mental health program could help women with advanced gynecologic or breast cancer manage their fear of the cancer coming back or getting worse. The program would have been compared to standard educational materials. However, the study w…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:17 UTC
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New study aims to help older breast cancer patients make chemo choices
Knowledge-focused OngoingThis study looks at how women aged 65 and older with early-stage breast cancer make decisions about chemotherapy. Researchers will interview patients and doctors to understand what information they need. The goal is to create a simple tool that helps patients and doctors weigh th…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:10 UTC
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Can we predict who will get nerve damage from chemo?
Knowledge-focused OngoingThis study aims to find out why some cancer patients develop nerve damage (tingling or numbness in hands and feet) from taxane chemotherapy. Researchers will track over 1,300 people with breast, lung, or ovarian cancer to see how age, gender, and other factors affect their risk. …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Jun 03, 2026 12:04 UTC