Can estrogen fight an aggressive breast cancer? new trial explores

NCT ID NCT03941730

First seen Nov 21, 2025 · Last updated May 15, 2026 · Updated 17 times

Summary

This study tests if the hormone estradiol can slow or shrink tumors in people with a specific type of triple negative breast cancer that has spread. The cancer must have a protein called ER beta, which may make it sensitive to estrogen. The goal is to see if this treatment can control the disease for at least 6 months.

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Contacts and locations

Locations

  • FHCC South Lake Union

    Seattle, Washington, 98109, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • UCSF Medical Center-Mission Bay

    San Francisco, California, 94158, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Washington Medical Center - Montlake

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.