New triple-drug attack shows promise against hard-to-treat breast cancer

NCT ID NCT05422794

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This early-phase trial tests whether adding an experimental drug (ZEN003694) to standard chemotherapy and immunotherapy is safe and can shrink tumors in people with advanced triple-negative breast cancer. About 57 participants will receive the combination. The goal is to find the best dose and see if the approach works better than chemotherapy alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston Medical Center

    RECRUITING

    Boston, Massachusetts, 02118, United States

    Contact

    Contact Phone: •••-•••-••••

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-••••

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact Email: •••••@•••••

  • NYU Langone Hospital - Long Island

    RECRUITING

    Mineola, New York, 11501, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt Breast Center at One Hundred Oaks

    RECRUITING

    Nashville, Tennessee, 37204, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.