New drug combo targets Hard-to-Treat HER2 cancers in early trial
NCT ID NCT07137416
First seen Jan 06, 2026 · Last updated Apr 24, 2026 · Updated 20 times
Summary
This early-phase study tests whether combining two drugs—pidnarulex and trastuzumab deruxtecan—is safe and effective for people with advanced breast cancer or other solid tumors that have a protein called HER2. The trial enrolls about 36 adults whose cancer has spread, cannot be removed by surgery, or has stopped responding to standard treatments. The goal is to find the best dose and check for side effects and tumor shrinkage.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Dana-Farber - Harvard Cancer Center LAO
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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