New drug combo shows promise for Hard-to-Treat cancers
NCT ID NCT05372640
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This early-phase study tests the safety and best dose of two drugs, ZEN003694 and abemaciclib, given together. It is for people with advanced breast cancer, NUT carcinoma, or other solid tumors that have spread or cannot be removed by surgery. The goal is to see if the combination can shrink or stabilize the cancer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Keck Medicine of USC Koreatown
RECRUITINGLos Angeles, California, 90020, United States
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Los Angeles General Medical Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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USC / Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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USC Norris Oncology/Hematology-Newport Beach
RECRUITINGNewport Beach, California, 92663, United States
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UT MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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