ANALGESIA
Clinical trials for ANALGESIA explained in plain language.
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Timing of scalp block may cut opioid use in brain surgery
Symptom relief Not yet recruitingThis study looks at whether giving a scalp nerve block before the surgeon makes the first cut (instead of after) can lower pain and the amount of strong painkillers needed during and after brain surgery. About 64 adults having craniotomy will be randomly assigned to one of two ti…
Matched conditions: ANALGESIA
Sponsor: Umraniye Education and Research Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:11 UTC
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Could a nerve block additive cut post-C-section pain?
Symptom relief Not yet recruitingThis study tests whether adding neostigmine to a standard numbing medicine (bupivacaine) in an ultrasound-guided abdominal wall block can provide better pain relief after cesarean delivery. About 58 women having planned C-sections will be randomly assigned to receive either the s…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated May 17, 2026 03:10 UTC
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New combo may cut opioids and confusion after brain surgery
Symptom relief Not yet recruitingThis study tests two methods—scalp nerve blocks and a sedative drug called dexmedetomidine—to see if they can reduce the need for strong opioid painkillers and prevent confusion after brain tumor surgery. About 2000 adults having elective brain surgery will be randomly assigned t…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:00 UTC
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Needle-Free pain relief: nasal spray could replace shots for kids in the ER
Symptom relief Not yet recruitingThis study tests two different nasal sprays (sufentanil and ketamine) to see which works better for severe pain from injuries like broken bones in children aged 6 to 17. Both sprays are given in the emergency room along with standard care. The goal is to find a fast, needle-free …
Matched conditions: ANALGESIA
Phase: PHASE2 • Sponsor: Fondation Lenval • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Heart surgery patients may get safer pain relief with tailored methadone
Symptom relief Not yet recruitingThis study aims to find the best way to use methadone for pain relief in adults over 60 having heart surgery. Researchers will use genetic information to personalize dosing, hoping to reduce side effects like nausea, breathing problems, and excessive sleepiness. The goal is to im…
Matched conditions: ANALGESIA
Sponsor: Kathirvel Subramaniam • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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Nerve block may cut Kids' opioid use after ACL surgery
Symptom relief Not yet recruitingThis study looks at whether a single shot of a numbing medicine (ropivacaine) near the nerves can lower pain and the need for narcotic pain pills in children after ACL knee surgery. About 160 kids aged 13 and older will be randomly assigned to get either the nerve block or no blo…
Matched conditions: ANALGESIA
Phase: PHASE2 • Sponsor: Texas Scottish Rite Hospital for Children • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New pain combo could cut opioid use after brain surgery
Symptom relief Not yet recruitingThis study tests a combination of pain medicines and local numbing to improve pain control after brain tumor surgery. The goal is to reduce the need for strong opioids, which can cause side effects and complications. About 2,000 adults having planned brain surgery will take part.…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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New drug cocktail aims to quiet ICU delirium without a breathing tube
Symptom relief Not yet recruitingThis study tests whether a combination of two sedative drugs, esketamine and dexmedetomidine, can safely and effectively reduce the time ICU patients spend in a state of severe confusion and agitation (hyperactive delirium) while they are on non-invasive breathing support. About …
Matched conditions: ANALGESIA
Phase: PHASE4 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Symptom relief
Last updated May 04, 2026 16:22 UTC