Laser vs radiofrequency: a new hope for knee pain relief?

NCT ID NCT07700784

Not yet recruiting Symptom relief Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether using a laser to ablate (destroy) specific nerves around the knee provides better pain relief than the standard radiofrequency method for people with chronic knee osteoarthritis. Fifty adults with persistent knee pain will receive one of the two procedures under ultrasound guidance. The study measures pain intensity using a standard scale to see which technique offers superior relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: laser genicular nerve ablation or conventional radiofrequency genicular nerve ablation
What this could lead to: If laser ablation proves more effective or safer than radiofrequency, it could offer a new, less invasive option for managing chronic knee pain from osteoarthritis.
What could go wrong: This is a small, early-stage trial with only 50 participants, so results may not apply broadly. Both procedures carry risks like infection or nerve damage, and pain relief may be temporary.

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis, knee pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA

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