New drug cocktail aims to quiet ICU delirium without a breathing tube
NCT ID NCT07377981
First seen Feb 01, 2026 · Last updated May 03, 2026 · Updated 13 times
Summary
This study tests whether a combination of two sedative drugs, esketamine and dexmedetomidine, can safely and effectively reduce the time ICU patients spend in a state of severe confusion and agitation (hyperactive delirium) while they are on non-invasive breathing support. About 132 adults will be randomly assigned to receive either the drug combo or standard care. The main goal is to see how long the delirium lasts, with a focus on avoiding the need for a breathing tube.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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