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Nerve blocks may slash opioid use after heart surgery

NCT ID NCT07692659

Symptom relief Sponsor: National Cancer Institute, Egypt Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This trial compares two ultrasound-guided nerve-block techniques for controlling pain during and after heart surgery. One method uses parasternal and rectus sheath blocks; the other uses an erector spinae plane block. The goal is to see which provides better pain relief and reduces the need for opioids, potentially leading to faster recovery. The study includes adults with moderate to high surgical risk (ASA III–IV) and excludes those with certain heart, blood, or liver conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (parasternal/rectus sheath block or erector spinae plane block)
What this could lead to
If one method proves better, it could become the standard for pain control after heart surgery, reducing opioid side effects and speeding recovery.
What could go wrong
This is a small, early-stage study (50 people) comparing two techniques, so results may not apply to all patients. Nerve blocks carry risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both sexes, * ASA III-IV patients * body mass index between 20- 35 kg/m2 * adult patients above 18 years old will be included in the study Exclusion Criteria: * Patients with global hypokinesia * ejection fraction \< 40% * low platelet count * coagulation impairment * deformity in the vertebral column * severe renal and hepatic impairment * any known allergy to the drugs used

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia Perioperative analgesia Regional block technique

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  2. A doctor treating you

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