Nerve blocks may slash opioid use after heart surgery

NCT ID NCT07692659

First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This trial compares two ultrasound-guided nerve-block techniques for controlling pain during and after heart surgery. One method uses parasternal and rectus sheath blocks; the other uses an erector spinae plane block. The goal is to see which provides better pain relief and reduces the need for opioids, potentially leading to faster recovery. The study includes adults with moderate to high surgical risk (ASA III–IV) and excludes those with certain heart, blood, or liver conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nerve block (parasternal/rectus sheath block or erector spinae plane block)
What this could lead to
If one method proves better, it could become the standard for pain control after heart surgery, reducing opioid side effects and speeding recovery.
What could go wrong
This is a small, early-stage study (50 people) comparing two techniques, so results may not apply to all patients. Nerve blocks carry risks like bleeding or infection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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