ANALGESIA

This study tests whether a targeted nerve block (retrolaminar block) provides better pain relief after lumbar discectomy than the standard method of injecting pain medicine into the surgical wound. 130 adults having elective single-level herniated disc surgery will be randomly as…

This study tests a single injection of F14, a long-acting form of the painkiller celecoxib, in 100 people undergoing total knee replacement. The goal is to see if it safely controls pain as part of a standard pain management plan. Participants receive the injection during surgery…

This study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. Ninety adults will receive one of the drugs or a placebo before spinal anesthesia. Researchers will measure anxiety levels and pain sc…

This study was designed to test a new pain medicine called HTX-011 in children and teens (ages 3 to 17) after hernia surgery. The goal was to see how well it controls pain and how safe it is. However, the study was withdrawn before any participants were enrolled, so no results ar…

This study tests whether a numbing injection near the glossopharyngeal nerve, combined with topical anesthesia, can help people recover faster after surgery for obstructive sleep apnea. The trial involves 80 adults with moderate to severe sleep apnea who are scheduled for palatop…

This study tests whether injecting a low dose of ketamine directly into the jaw during surgery can reduce pain, swelling, and nausea afterward. Forty adults having corrective jaw surgery will receive either ketamine plus standard anesthetic or standard anesthetic alone. Researche…

This study aimed to see if using real-time ultrasound during a thoracic epidural block makes the procedure more reliable. It was designed for adults with chest or abdominal pain or rib fractures. The study was withdrawn before enrolling any participants, so no results are availab…

This study looks back at the medical records of 600 adults who received a single shot of morphine into the spine before surgery. The goal is to understand how often side effects like breathing problems, itching, and nausea happen. By learning more, doctors hope to make pain manag…

This study looks at how small differences in certain genes affect how people respond to propofol, a common anesthesia drug. Researchers want to understand why some people wake up faster or have more side effects than others. The goal is to help doctors give safer, more personaliz…