Could a ketamine injection during jaw surgery cut Post-Op pain?

NCT ID NCT07066306

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting a low dose of ketamine directly into the jaw during surgery can reduce pain, swelling, and nausea afterward. Forty adults having corrective jaw surgery will receive either ketamine plus standard anesthetic or standard anesthetic alone. Researchers will measure pain scores, swelling, and the need for extra pain medicine over the first week.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketamine

What this could lead to

If it works, this could offer a simple way to reduce pain and swelling after jaw surgery without strong side effects.

What could go wrong

This is a small, early-stage study with only 40 people, so results may not apply widely. Ketamine can cause side effects like dizziness or nausea.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia Dentofacial Deformities Nausea pain agnosia Postoperative Nausea and Vomiting Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bezmialem Vakıf Universty

    Istanbul, Fatih, 34093, Turkey (Türkiye)