Fish oil could cut morphine needs after surgery, new trial hopes

NCT ID NCT07657468

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking omega-3 fatty acids before and after gallbladder surgery can lower the amount of morphine needed for pain. Forty adults will receive either omega-3 supplements or a placebo, plus a small dose of morphine after surgery. Researchers will measure total morphine use over 24 hours and track pain, nausea, and other side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Omega-3 fatty acids
What this could lead to
If it works, this could offer a simple, natural way to reduce morphine use after surgery, potentially lowering side effects like nausea and drowsiness.
What could go wrong
This is a small, early-phase study with only 40 participants, so results may not apply widely. Omega-3 may not significantly reduce pain or morphine needs.

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National University of La Rioja

    La Rioja, La Rioja Province, F5300ALR, Argentina

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