New pain cocktail aims to cut opioid use after brain surgery
NCT ID NCT06406829
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a combination of two pain-relief methods—a sedative drug called dexmedetomidine and a local anesthetic injected into the scalp—for people undergoing brain tumor surgery. The goal is to see if this approach reduces the need for strong opioid painkillers after surgery, while keeping patients safe and comfortable. The trial will enroll 2,000 adults aged 18 to 65 at a single hospital in China.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine and local anesthetic (liposomal bupivacaine)
- What this could lead to
- If successful, this could provide a standard pain management plan that reduces opioid use and speeds recovery after brain surgery.
- What could go wrong
- This is a single-center trial that hasn't started recruiting yet. Results may not apply to all hospitals or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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