New pain block cocktail may cut opioid use after breast surgery

NCT ID NCT07683416

Not yet recruiting Symptom relief Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This trial compares two ultrasound-guided nerve blocks—serratus-intercostal and erector spinae—both using a mix of bupivacaine and dexmedetomidine to control pain after mastectomy. The goal is to see which block reduces the need for morphine and improves pain scores. Seventy women undergoing unilateral mastectomy will participate, with outcomes measured over the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine and bupivacaine
What this could lead to: If one block proves better, it could offer a more effective, opioid-sparing pain control method for mastectomy patients.
What could go wrong: This is a small, early-stage comparison; results may not apply broadly, and nerve blocks carry risks like infection or incomplete pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANALGESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.