Pulmonary embolism

People who have spine surgery for cancer that has spread are at high risk for dangerous blood clots in the legs or lungs. Currently, blood-thinning medicine is stopped when patients leave the hospital. This trial tests whether taking apixaban (Eliquis) by mouth for 30 days after …

This study tests a new device called the Vibrato Aspiration System, designed to remove blood clots from the lungs in people with acute pulmonary embolism (a sudden blockage in the lung artery). The trial includes up to 10 adults aged 18 to 75 who have had symptoms for 14 days or …

This pilot study tests a new catheter device designed to deliver clot-dissolving medication directly to blood clots in the lungs of adults with intermediate-risk pulmonary embolism. The goal is to see if the device can be used safely and as intended. All 20 participants will rece…

This study is testing a new device called the eTrieve PE Kit to remove blood clots from the lungs in people with a moderate-risk pulmonary embolism. About 130 adults will be enrolled to see if the device is safe and effective at improving blood flow and reducing complications. Th…

This study explores whether an additional CT scan of the heart, taken right after a standard scan for lung clots, can effectively detect blood clots in the left atrial appendage (LAA) in people with atrial fibrillation. Currently, detecting these clots requires a more involved pr…

This study looks at whether comparing a patient's previous pulmonary artery pressure (PAP) reading with one taken during an ER visit can help doctors quickly identify a pulmonary embolism (a blood clot in the lung). Researchers will review records of 80 adults who come to the ER …

This study is testing whether a simple, 1-minute heart recording (ECG) analyzed by a computer can help detect pulmonary embolism, a serious blood clot in the lungs. Researchers will enroll 500 adults who need to be checked for this condition. The goal is to see if this quick, non…

This study will test a new, non-invasive bedside scan (3D-EIT) to see if it can accurately diagnose and monitor pulmonary embolism (blood clots in the lungs) without using radiation. About 115 adults with and without clots will participate. The goal is to provide a safer, easier …

This study explores whether a low-dose CT scan without contrast dye can accurately detect pulmonary embolism (blood clots in the lungs). Researchers will enroll 750 adults suspected of having a clot and add two very low-radiation CT scans to their standard dye-based scan. The goa…

This study aims to see if a simple breath test can help doctors quickly tell which patients with chest pain are at high risk for a heart attack or other serious condition. Researchers will collect breath samples from 6,000 adults coming to the emergency room with chest pain and a…

This study looks at whether new blood markers (TAT, PIC, TM, t-PAIC) can help diagnose and monitor acute pulmonary embolism (a dangerous blood clot in the lungs). Researchers will test 200 newly diagnosed patients and 200 healthy controls to see how accurate these markers are. Th…

This study looks at whether people with a moderate-risk blood clot in the lungs can be safely treated at home instead of staying in the hospital. About 568 adults will be randomly assigned to either go home early or receive standard hospital care. The goal is to see if home treat…

This study is a large international registry that will look back at the medical records of about 1,000 adults who were treated with the AngioVac system, a device that uses suction to remove blood clots, infected tissue, or other unwanted material from the heart and major blood ve…

People with interstitial lung disease (ILD) can suddenly get much worse, but it is hard to tell if the cause is a lung flare-up or a blood clot in the lungs (pulmonary embolism). This observational study will follow 70 adults with ILD who come to the hospital with worsening breat…

This study follows 25,000 people referred to a specialized heart clinic with symptoms like chest pain or shortness of breath. Researchers will track which heart conditions are actually diagnosed and how patients are evaluated. The goal is to improve diagnostic accuracy and unders…

This study tests a decision aid for people who have had a first blood clot and must decide whether to stop or continue blood thinners after at least 3 months of treatment. The aid provides balanced information on risks and benefits and helps clarify personal values. Researchers w…

This study will collect data from 624 patients in respiratory intermediate care units (RICUs) across Catalonia to build a model that predicts 30-day survival. Researchers will also test an artificial intelligence approach and create a quick app for doctors. The goal is to better …

This study looks at whether a routine blood test (RDW) can help doctors quickly identify how well the heart and lungs are working together in people with a sudden lung clot (pulmonary embolism). Researchers will measure RDW and compare it to an ultrasound measure of heart-lung co…

This study looks at 1,300 people with moderate-risk pulmonary embolism (blood clots in the lungs) to compare three treatments: blood thinners, clot-busting drugs, and mechanical clot removal. Researchers will track deaths, heart recovery, bleeding risks, and quality of life over …

This study looks at 50 adults with acute pulmonary embolism (a blood clot in the lungs) to compare different methods used to diagnose and predict outcomes. Researchers will analyze clinical scores, lab tests, and CT scans from patients in various hospital departments. The goal is…

This study watches 100 adults with severe pulmonary embolism (blood clots in the lungs) during a procedure to remove the clots. The goal is to learn when and why heart or breathing problems happen during the procedure, so doctors can better prevent them and improve patient safety…

This study watches 300 ICU patients to see how often blood clots caused by catheters remain in the vein after the catheter is taken out. Researchers will track risk factors and whether these clots lead to serious issues like lung clots or long-term vein damage. No new treatments …

This study looks at whether certain natural markers on red blood cells, called Lewis antigens, are more common in people who have had blood clots in their veins. Researchers will test 100 adults with a history of deep vein thrombosis and record their other clot risk factors. The …

This study tests a computer tool that gently reminds doctors when they are about to order a CT scan for a possible pulmonary embolism (a blood clot in the lung) against clinical guidelines. The tool only appears when the order may not be needed, giving doctors a chance to reconsi…

This study will collect information from 1,200 patients in the French West Indies and Guiana who received ECMO, a machine that helps the heart and lungs. Researchers aim to track survival rates and complications to better understand how ECMO works in this region. The study does n…