Can a vacuum device safely suck out dangerous heart clots? a global registry investigates
NCT ID NCT07769320
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This study is a large international registry that will look back at the medical records of about 1,000 adults who were treated with the AngioVac system, a device that uses suction to remove blood clots, infected tissue, or other unwanted material from the heart and major blood vessels. The goal is to understand how safe and effective the device is in everyday clinical practice across a wide range of conditions, including heart infections and clots in the heart or lungs. By analyzing outcomes and complications, researchers hope to identify which patients benefit most and to develop best-practice recommendations for its use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AngioVac aspiration system (a device used to suction out unwanted material from blood vessels and heart chambers)
- What this could lead to
- If successful, this study could provide clearer guidance on when and how to use the AngioVac device, potentially improving outcomes for people with dangerous blood clots or heart infections.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be limited by incomplete data or differences in how centers use the device.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Charité - Universitätsmedizin Berlin, Deutsches Herzzentrum der Charité, Department of Cardiothoracic and Vascular Surgery
Berlin, 13353, Germany
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